| Reaction Details |
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 | Report a problem with these data |
| Target | Bcl-2-like protein 2 |
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| Ligand | BDBM33135 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Multiplexed dose response screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-W. |
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| EC50 | 27940±n/a nM |
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| Citation |  PubChem, PC Multiplexed dose response screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-W. PubChem Bioassay(2008)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| Bcl-2-like protein 2 |
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| Name: | Bcl-2-like protein 2 |
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| Synonyms: | Apoptosis regulator Bcl-W | B2CL2_HUMAN | BCL-W | BCL2L2 | BCLW | Bcl-2-like protein 2 | Bcl2-L-2 | KIAA0271 |
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| Type: | Protein |
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| Mol. Mass.: | 20742.61 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 193 |
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| Sequence: | MATPASAPDTRALVADFVGYKLRQKGYVCGAGPGEGPAADPLHQAMRAAGDEFETRFRRT
FSDLAAQLHVTPGSAQQRFTQVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEPLVG
QVQEWMVAYLETQLADWIHSSGGWAEFTALYGDGALEEARRLREGNWASVRTVLTGAVAL
GALVTVGAFFASK
|
|
|
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| BDBM33135 |
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| n/a |
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| Name | BDBM33135 |
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| Synonyms: | 3-[(E)-3-(3,4-dimethylphenyl)-1-oxoprop-2-enyl]-2-hydroxy-1-cyclohepta-2,4,6-trienone | 3-[(E)-3-(3,4-dimethylphenyl)acryloyl]-2-hydroxy-cyclohepta-2,4,6-trien-1-one | 3-[(E)-3-(3,4-dimethylphenyl)prop-2-enoyl]-2-hydroxycyclohepta-2,4,6-trien-1-one | 3-[(E)-3-(3,4-dimethylphenyl)prop-2-enoyl]-2-oxidanyl-cyclohepta-2,4,6-trien-1-one | 3-[3-(3,4-dimethylphenyl)acryloyl]-2-hydroxy-2,4,6-cycloheptatrien-1-one | MLS000756172 | SMR000229847 | cid_6110289 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H16O3 |
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| Mol. Mass. | 280.3178 |
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| SMILES | Cc1ccc(\C=C\C(=O)c2ccccc(=O)c2O)cc1C |
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| Structure | 
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