Reaction Details |
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Target | Signal transducer and activator of transcription 3 [702-738,740-752] |
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Ligand | BDBM46350 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Dose response cell-based assay to measure STAT3 inhibition |
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IC50 | 2901±n/a nM |
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Citation | PubChem, PC Dose response cell-based assay to measure STAT3 inhibition PubChem Bioassay(2008)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Signal transducer and activator of transcription 3 [702-738,740-752] |
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Name: | Signal transducer and activator of transcription 3 [702-738,740-752] |
Synonyms: | APRF | STAT3 | STAT3_HUMAN |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 5263.93 |
Organism: | Homo sapiens (Human) |
Description: | gi_13272532 |
Residue: | 50 |
Sequence: | AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
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BDBM46350 |
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n/a |
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Name | BDBM46350 |
Synonyms: | 4-[[4-(morpholinomethyl)benzoyl]amino]benzoic acid ethyl ester | 4-[[[4-(4-morpholinylmethyl)phenyl]-oxomethyl]amino]benzoic acid ethyl ester | MLS000061256 | SMR000070125 | cid_1257531 | ethyl 4-[[4-(morpholin-4-ylmethyl)benzoyl]amino]benzoate | ethyl 4-[[4-(morpholin-4-ylmethyl)phenyl]carbonylamino]benzoate | ethyl 4-{[4-(4-morpholinylmethyl)benzoyl]amino}benzoate |
Type | Small organic molecule |
Emp. Form. | C21H24N2O4 |
Mol. Mass. | 368.4263 |
SMILES | CCOC(=O)c1ccc(NC(=O)c2ccc(CN3CCOCC3)cc2)cc1 |
Structure |
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