Reaction Details |
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Target | Signal transducer and activator of transcription 3 [702-738,740-752] |
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Ligand | BDBM46356 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Dose response cell-based assay to measure STAT3 inhibition |
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IC50 | 700±n/a nM |
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Citation | PubChem, PC Dose response cell-based assay to measure STAT3 inhibition PubChem Bioassay(2008)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Signal transducer and activator of transcription 3 [702-738,740-752] |
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Name: | Signal transducer and activator of transcription 3 [702-738,740-752] |
Synonyms: | APRF | STAT3 | STAT3_HUMAN |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 5263.93 |
Organism: | Homo sapiens (Human) |
Description: | gi_13272532 |
Residue: | 50 |
Sequence: | AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
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BDBM46356 |
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n/a |
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Name | BDBM46356 |
Synonyms: | DIGITOXIN | MLS000069787 | SMR000058529 | US10668094, Compound Digitoxin | cid_441207 |
Type | Small organic molecule |
Emp. Form. | C41H64O13 |
Mol. Mass. | 764.9391 |
SMILES | C[C@H]1O[C@H](C[C@H](O)[C@@H]1O)O[C@H]1[C@@H](O)C[C@H](O[C@H]2[C@@H](O)C[C@H](O[C@H]3CC[C@@]4(C)[C@H](CC[C@@H]5[C@@H]4CC[C@]4(C)[C@H](CC[C@]54O)C4=CC(=O)OC4)C3)O[C@@H]2C)O[C@@H]1C |t:45| |
Structure |
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