Reaction Details |
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Target | Signal transducer and activator of transcription 3 [702-738,740-752] |
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Ligand | BDBM43504 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Dose response counterscreen for STAT1 inhibitors: cell-based high throughput assay to measure STAT3 inhibition |
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IC50 | >55700±n/a nM |
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Citation | PubChem, PC Dose response counterscreen for STAT1 inhibitors: cell-based high throughput assay to measure STAT3 inhibition PubChem Bioassay(2008)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Signal transducer and activator of transcription 3 [702-738,740-752] |
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Name: | Signal transducer and activator of transcription 3 [702-738,740-752] |
Synonyms: | APRF | STAT3 | STAT3_HUMAN |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 5263.93 |
Organism: | Homo sapiens (Human) |
Description: | gi_13272532 |
Residue: | 50 |
Sequence: | AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
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BDBM43504 |
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n/a |
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Name | BDBM43504 |
Synonyms: | 5-amino-3-(2-methylphenyl)-1,2-oxazole-4-carbonitrile | 5-amino-3-(2-methylphenyl)-4-isoxazolecarbonitrile | 5-amino-3-(2-methylphenyl)isoxazole-4-carbonitrile | 5-amino-3-(o-tolyl)isoxazole-4-carbonitrile | 5-azanyl-3-(2-methylphenyl)-1,2-oxazole-4-carbonitrile | MLS000045809 | SMR000028206 | cid_3236239 |
Type | Small organic molecule |
Emp. Form. | C11H9N3O |
Mol. Mass. | 199.2087 |
SMILES | Cc1ccccc1-c1noc(N)c1C#N |
Structure |
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