BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetSignal transducer and activator of transcription 3 [702-738,740-752]
LigandBDBM43508
Substrate/Competitorn/a
Meas. Tech.Dose response counterscreen for STAT1 inhibitors: cell-based high throughput assay to measure STAT3 inhibition
IC50>55700±n/a nM
Citation PubChem, PC Dose response counterscreen for STAT1 inhibitors: cell-based high throughput assay to measure STAT3 inhibition PubChem Bioassay(2008)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Signal transducer and activator of transcription 3 [702-738,740-752]
Name:Signal transducer and activator of transcription 3 [702-738,740-752]
Synonyms:APRF | STAT3 | STAT3_HUMAN
Type:Enzyme Catalytic Domain
Mol. Mass.:5263.93
Organism:Homo sapiens (Human)
Description:gi_13272532
Residue:50
Sequence:
AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM43508
n/a
NameBDBM43508
Synonyms:MLS000526191 | N-[1-(4-Methyl-6-oxo-6H-pyrimidin-1-yl)-2-oxo-2-phenyl-ethyl]-benzamide | N-[1-(4-methyl-6-oxidanylidene-pyrimidin-1-yl)-2-oxidanylidene-2-phenyl-ethyl]benzamide | N-[1-(4-methyl-6-oxo-1-pyrimidinyl)-2-oxo-2-phenylethyl]benzamide | N-[1-(4-methyl-6-oxopyrimidin-1-yl)-2-oxo-2-phenylethyl]benzamide | N-[2-keto-1-(6-keto-4-methyl-pyrimidin-1-yl)-2-phenyl-ethyl]benzamide | SMR000116665 | cid_2802825
TypeSmall organic molecule
Emp. Form.C20H17N3O3
Mol. Mass.347.3673
SMILESCc1cc(=O)n(cn1)C(NC(=O)c1ccccc1)C(=O)c1ccccc1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: