Reaction Details |
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Target | Signal transducer and activator of transcription 3 [702-738,740-752] |
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Ligand | BDBM43508 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Dose response counterscreen for STAT1 inhibitors: cell-based high throughput assay to measure STAT3 inhibition |
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IC50 | >55700±n/a nM |
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Citation | PubChem, PC Dose response counterscreen for STAT1 inhibitors: cell-based high throughput assay to measure STAT3 inhibition PubChem Bioassay(2008)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Signal transducer and activator of transcription 3 [702-738,740-752] |
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Name: | Signal transducer and activator of transcription 3 [702-738,740-752] |
Synonyms: | APRF | STAT3 | STAT3_HUMAN |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 5263.93 |
Organism: | Homo sapiens (Human) |
Description: | gi_13272532 |
Residue: | 50 |
Sequence: | AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
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BDBM43508 |
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n/a |
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Name | BDBM43508 |
Synonyms: | MLS000526191 | N-[1-(4-Methyl-6-oxo-6H-pyrimidin-1-yl)-2-oxo-2-phenyl-ethyl]-benzamide | N-[1-(4-methyl-6-oxidanylidene-pyrimidin-1-yl)-2-oxidanylidene-2-phenyl-ethyl]benzamide | N-[1-(4-methyl-6-oxo-1-pyrimidinyl)-2-oxo-2-phenylethyl]benzamide | N-[1-(4-methyl-6-oxopyrimidin-1-yl)-2-oxo-2-phenylethyl]benzamide | N-[2-keto-1-(6-keto-4-methyl-pyrimidin-1-yl)-2-phenyl-ethyl]benzamide | SMR000116665 | cid_2802825 |
Type | Small organic molecule |
Emp. Form. | C20H17N3O3 |
Mol. Mass. | 347.3673 |
SMILES | Cc1cc(=O)n(cn1)C(NC(=O)c1ccccc1)C(=O)c1ccccc1 |
Structure |
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