| Reaction Details |
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 | Report a problem with these data |
| Target | Signal transducer and activator of transcription 3 [702-738,740-752] |
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| Ligand | BDBM43518 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose response counterscreen for STAT1 inhibitors: cell-based high throughput assay to measure STAT3 inhibition |
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| IC50 | 20310±n/a nM |
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| Citation |  PubChem, PC Dose response counterscreen for STAT1 inhibitors: cell-based high throughput assay to measure STAT3 inhibition PubChem Bioassay(2008)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Signal transducer and activator of transcription 3 [702-738,740-752] |
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| Name: | Signal transducer and activator of transcription 3 [702-738,740-752] |
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| Synonyms: | APRF | STAT3 | STAT3_HUMAN |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 5263.93 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_13272532 |
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| Residue: | 50 |
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| Sequence: | AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
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| BDBM43518 |
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| n/a |
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| Name | BDBM43518 |
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| Synonyms: | 2-[(E)-1-(benzenesulfonyl)-2-(3-methylphenyl)ethenyl]-1H-benzimidazole | 2-[(E)-1-besyl-2-(m-tolyl)vinyl]-1H-benzimidazole | 2-[(E)-2-(3-methylphenyl)-1-(phenylsulfonyl)ethenyl]-1H-benzimidazole | MLS000391257 | SMR000260294 | cid_6265504 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H18N2O2S |
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| Mol. Mass. | 374.456 |
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| SMILES | Cc1cccc(\C=C(/c2nc3ccccc3[nH]2)S(=O)(=O)c2ccccc2)c1 |
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| Structure | 
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