| Reaction Details |
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 | Report a problem with these data |
| Target | Mannose-6-phosphate isomerase |
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| Ligand | BDBM46619 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Confirmation of compounds inhibiting phosphomannose isomerase (PMI) via a fluorescence intensity assay. |
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| IC50 | 3030±n/a nM |
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| Citation |  PubChem, PC Confirmation of compounds inhibiting phosphomannose isomerase (PMI) via a fluorescence intensity assay. PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Mannose-6-phosphate isomerase |
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| Name: | Mannose-6-phosphate isomerase |
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| Synonyms: | MPI | MPI protein | MPI_HUMAN | Mannose-6-phosphate isomerase | PMI1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 46651.35 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1448919 |
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| Residue: | 423 |
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| Sequence: | MAAPRVFPLSCAVQQYAWGKMGSNSEVARLLASSDPLAQIAEDKPYAELWMGTHPRGDAK
ILDNRISQKTLSQWIAENQDSLGSKVKDTFNGNLPFLFKVLSVETPLSIQAHPNKELAEK
LHLQAPQHYPDANHKPEMAIALTPFQGLCGFRPVEEIVTFLKKVPEFQFLIGDEAATHLK
QTMSHDSQAVASSLQSCFSHLMKSEKKVVVEQLNLLVKRISQQAAAGNNMEDIFGELLLQ
LHQQYPGDIGCFAIYFLNLLTLKPGEAMFLEANVPHAYLKGDCVECMACSDNTVRAGLTP
KFIDVPTLCEMLSYTPSSSKDRLFLPTRSQEDPYLSIYDPPVPDFTIMKTEVPGSVTEYK
VLALDSASILLMVQGTVIASTPTTQTPIPLQRGGVLFIGANESVSLKLTEPKDLLIFRAC
CLL
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| BDBM46619 |
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| n/a |
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| Name | BDBM46619 |
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| Synonyms: | 2-(3-chloranyl-2-methyl-phenyl)-6-nitro-4-[2,2,2-tris(fluoranyl)ethoxy]-1,2-benzothiazol-3-one | 2-(3-chloro-2-methyl-phenyl)-6-nitro-4-(2,2,2-trifluoroethoxy)-1,2-benzothiazol-3-one | 2-(3-chloro-2-methylphenyl)-6-nitro-4-(2,2,2-trifluoroethoxy)-1,2-benzothiazol-3-one | MLS-0315770.0001 | cid_1510390 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H10ClF3N2O4S |
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| Mol. Mass. | 418.775 |
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| SMILES | Cc1c(Cl)cccc1-n1sc2cc(cc(OCC(F)(F)F)c2c1=O)[N+]([O-])=O |
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| Structure | 
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