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TargetMannose-6-phosphate isomerase
LigandBDBM46044
Substrate/Competitorn/a
Meas. Tech.Confirmation of compounds inhibiting phosphomannose isomerase (PMI) via a fluorescence intensity assay.
IC50 4930±n/a nM
Citation PubChem, PC Confirmation of compounds inhibiting phosphomannose isomerase (PMI) via a fluorescence intensity assay. PubChem Bioassay(2010)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Mannose-6-phosphate isomerase
Name:Mannose-6-phosphate isomerase
Synonyms:MPI | MPI protein | MPI_HUMAN | Mannose-6-phosphate isomerase | PMI1
Type:PROTEIN
Mol. Mass.:46651.35
Organism:Homo sapiens (Human)
Description:ChEMBL_1448919
Residue:423
Sequence:
MAAPRVFPLSCAVQQYAWGKMGSNSEVARLLASSDPLAQIAEDKPYAELWMGTHPRGDAK
ILDNRISQKTLSQWIAENQDSLGSKVKDTFNGNLPFLFKVLSVETPLSIQAHPNKELAEK
LHLQAPQHYPDANHKPEMAIALTPFQGLCGFRPVEEIVTFLKKVPEFQFLIGDEAATHLK
QTMSHDSQAVASSLQSCFSHLMKSEKKVVVEQLNLLVKRISQQAAAGNNMEDIFGELLLQ
LHQQYPGDIGCFAIYFLNLLTLKPGEAMFLEANVPHAYLKGDCVECMACSDNTVRAGLTP
KFIDVPTLCEMLSYTPSSSKDRLFLPTRSQEDPYLSIYDPPVPDFTIMKTEVPGSVTEYK
VLALDSASILLMVQGTVIASTPTTQTPIPLQRGGVLFIGANESVSLKLTEPKDLLIFRAC
CLL
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  Blast E-value cutoff:
BDBM46044
n/a
NameBDBM46044
Synonyms:3-(3-keto-1,2-benzothiazol-2-yl)benzoic acid methyl ester | 3-(3-oxo-1,2-benzothiazol-2-yl)benzoic acid methyl ester | MLS-0315861.0001 | cid_25067463 | methyl 3-(3-oxidanylidene-1,2-benzothiazol-2-yl)benzoate | methyl 3-(3-oxo-1,2-benzothiazol-2-yl)benzoate
TypeSmall organic molecule
Emp. Form.C15H11NO3S
Mol. Mass.285.318
SMILESCOC(=O)c1cccc(c1)-n1sc2ccccc2c1=O
Structure
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