| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Mannose-6-phosphate isomerase |
|---|
| Ligand | BDBM33086 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Confirmation of compounds inhibiting phosphomannose isomerase (PMI) via a fluorescence intensity assay. |
|---|
| IC50 | 3120±n/a nM |
|---|
| Citation |  PubChem, PC Confirmation of compounds inhibiting phosphomannose isomerase (PMI) via a fluorescence intensity assay. PubChem Bioassay(2010)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Mannose-6-phosphate isomerase |
|---|
| Name: | Mannose-6-phosphate isomerase |
|---|
| Synonyms: | MPI | MPI protein | MPI_HUMAN | Mannose-6-phosphate isomerase | PMI1 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 46651.35 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1448919 |
|---|
| Residue: | 423 |
|---|
| Sequence: | MAAPRVFPLSCAVQQYAWGKMGSNSEVARLLASSDPLAQIAEDKPYAELWMGTHPRGDAK
ILDNRISQKTLSQWIAENQDSLGSKVKDTFNGNLPFLFKVLSVETPLSIQAHPNKELAEK
LHLQAPQHYPDANHKPEMAIALTPFQGLCGFRPVEEIVTFLKKVPEFQFLIGDEAATHLK
QTMSHDSQAVASSLQSCFSHLMKSEKKVVVEQLNLLVKRISQQAAAGNNMEDIFGELLLQ
LHQQYPGDIGCFAIYFLNLLTLKPGEAMFLEANVPHAYLKGDCVECMACSDNTVRAGLTP
KFIDVPTLCEMLSYTPSSSKDRLFLPTRSQEDPYLSIYDPPVPDFTIMKTEVPGSVTEYK
VLALDSASILLMVQGTVIASTPTTQTPIPLQRGGVLFIGANESVSLKLTEPKDLLIFRAC
CLL
|
|
|
|---|
| BDBM33086 |
|---|
| n/a |
|---|
| Name | BDBM33086 |
|---|
| Synonyms: | (4-chloro-2,5-dimethoxy-phenyl)-(4-chlorodithiazol-5-ylidene)amine | 4-chloranyl-N-(4-chloranyl-2,5-dimethoxy-phenyl)-1,2,3-dithiazol-5-imine | 4-chloro-N-(4-chloro-2,5-dimethoxyphenyl)-5-dithiazolimine | 4-chloro-N-(4-chloro-2,5-dimethoxyphenyl)dithiazol-5-imine | MLS000519625 | SMR000130043 | cid_602897 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C10H8Cl2N2O2S2 |
|---|
| Mol. Mass. | 323.219 |
|---|
| SMILES | COc1cc(\N=c2\ssnc2Cl)c(OC)cc1Cl |
|---|
| Structure | 
|
|---|
Search and Browse
