| Reaction Details |
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 | Report a problem with these data |
| Target | Mucolipin-3 |
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| Ligand | BDBM46818 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose response cell-based high-throughput screening assay for agonists of the transient receptor potential channel ML3 (TRPML3) |
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| EC50 | 1160±n/a nM |
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| Citation |  PubChem, PC Dose response cell-based high-throughput screening assay for agonists of the transient receptor potential channel ML3 (TRPML3) PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| Mucolipin-3 |
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| Name: | Mucolipin-3 |
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| Synonyms: | MCLN3_HUMAN | MCOLN3 | MCOLN3 protein |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 64244.09 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q8TDD5 |
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| Residue: | 553 |
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| Sequence: | MADPEVVVSSCSSHEEENRCNFNQQTSPSEELLLEDQMRRKLKFFFMNPCEKFWARGRKP
WKLAIQILKIAMVTIQLVLFGLSNQMVVAFKEENTIAFKHLFLKGYMDRMDDTYAVYTQS
DVYDQLIFAVNQYLQLYNVSVGNHAYENKGTKQSAMAICQHFYKRGNIYPGNDTFDIDPE
IETECFFVEPDEPFHIGTPAENKLNLTLDFHRLLTVELQFKLKAINLQTVRHQELPDCYD
FTLTITFDNKAHSGRIKISLDNDISIRECKDWHVSGSIQKNTHYMMIFDAFVILTCLVSL
ILCIRSVIRGLQLQQEFVNFFLLHYKKEVSVSDQMEFVNGWYIMIIISDILTIIGSILKM
EIQAKSLTSYDVCSILLGTSTMLVWLGVIRYLGFFAKYNLLILTLQAALPNVIRFCCCAA
MIYLGYCFCGWIVLGPYHDKFRSLNMVSECLFSLINGDDMFATFAKMQQKSYLVWLFSRI
YLYSFISLFIYMILSLFIALITDTYETIKQYQQDGFPETELRTFISECKDLPNSGKYRLE
DDPPVSLFCCCKK
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| BDBM46818 |
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| n/a |
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| Name | BDBM46818 |
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| Synonyms: | MLS000074627 | N-Cyclopropyl-4-(2-ethyl-piperidine-1-sulfonyl)-N-thiophen-2-ylmethyl-benzenesulfonamide | N-cyclopropyl-4-(2-ethylpiperidin-1-yl)sulfonyl-N-(thiophen-2-ylmethyl)benzenesulfonamide | N-cyclopropyl-4-(2-ethylpiperidino)sulfonyl-N-(2-thenyl)benzenesulfonamide | N-cyclopropyl-4-[(2-ethyl-1-piperidinyl)sulfonyl]-N-(thiophen-2-ylmethyl)benzenesulfonamide | SMR000003599 | cid_645530 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H28N2O4S3 |
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| Mol. Mass. | 468.653 |
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| SMILES | CCC1CCCCN1S(=O)(=O)c1ccc(cc1)S(=O)(=O)N(Cc1cccs1)C1CC1 |
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| Structure | 
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