Ki Summary

Reaction Details

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Target

Mucolipin-3

Ligand

BDBM46827

Substrate/Competitor

n/a

Meas. Tech.

Dose response cell-based high-throughput screening assay for agonists of the transient receptor potential channel ML3 (TRPML3)

EC50

1360±n/a nM

Citation

PubChem, PC Dose response cell-based high-throughput screening assay for agonists of the transient receptor potential channel ML3 (TRPML3) PubChem Bioassay(2009)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Mucolipin-3

Name:

Mucolipin-3

Synonyms:

MCLN3_HUMAN | MCOLN3 | MCOLN3 protein

Type:

Enzyme Catalytic Domain

Mol. Mass.:

64244.09

Organism:

Homo sapiens (Human)

Description:

Q8TDD5

Residue:

553

Sequence:

MADPEVVVSSCSSHEEENRCNFNQQTSPSEELLLEDQMRRKLKFFFMNPCEKFWARGRKP
WKLAIQILKIAMVTIQLVLFGLSNQMVVAFKEENTIAFKHLFLKGYMDRMDDTYAVYTQS
DVYDQLIFAVNQYLQLYNVSVGNHAYENKGTKQSAMAICQHFYKRGNIYPGNDTFDIDPE
IETECFFVEPDEPFHIGTPAENKLNLTLDFHRLLTVELQFKLKAINLQTVRHQELPDCYD
FTLTITFDNKAHSGRIKISLDNDISIRECKDWHVSGSIQKNTHYMMIFDAFVILTCLVSL
ILCIRSVIRGLQLQQEFVNFFLLHYKKEVSVSDQMEFVNGWYIMIIISDILTIIGSILKM
EIQAKSLTSYDVCSILLGTSTMLVWLGVIRYLGFFAKYNLLILTLQAALPNVIRFCCCAA
MIYLGYCFCGWIVLGPYHDKFRSLNMVSECLFSLINGDDMFATFAKMQQKSYLVWLFSRI
YLYSFISLFIYMILSLFIALITDTYETIKQYQQDGFPETELRTFISECKDLPNSGKYRLE
DDPPVSLFCCCKK

BDBM46827

n/a

Name

BDBM46827

Synonyms:

5-chloranyl-N-(2-morpholin-4-ylphenyl)thiophene-2-sulfonamide | 5-chloro-N-(2-morpholin-4-ylphenyl)thiophene-2-sulfonamide | 5-chloro-N-(2-morpholinophenyl)thiophene-2-sulfonamide | 5-chloro-N-[2-(4-morpholinyl)phenyl]-2-thiophenesulfonamide | MLS000054019 | SMR000063811 | cid_2124908

Type

Small organic molecule

Emp. Form.

C14H15ClN2O3S2

Mol. Mass.

358.864

SMILES

Clc1ccc(s1)S(=O)(=O)Nc1ccccc1N1CCOCC1

Structure