Ki Summary

Reaction Details

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Target

Mucolipin-3

Ligand

BDBM46838

Substrate/Competitor

n/a

Meas. Tech.

Dose response cell-based high-throughput screening assay for agonists of the transient receptor potential channel ML3 (TRPML3)

EC50

26500±n/a nM

Citation

PubChem, PC Dose response cell-based high-throughput screening assay for agonists of the transient receptor potential channel ML3 (TRPML3) PubChem Bioassay(2009)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Mucolipin-3

Name:

Mucolipin-3

Synonyms:

MCLN3_HUMAN | MCOLN3 | MCOLN3 protein

Type:

Enzyme Catalytic Domain

Mol. Mass.:

64244.09

Organism:

Homo sapiens (Human)

Description:

Q8TDD5

Residue:

553

Sequence:

MADPEVVVSSCSSHEEENRCNFNQQTSPSEELLLEDQMRRKLKFFFMNPCEKFWARGRKP
WKLAIQILKIAMVTIQLVLFGLSNQMVVAFKEENTIAFKHLFLKGYMDRMDDTYAVYTQS
DVYDQLIFAVNQYLQLYNVSVGNHAYENKGTKQSAMAICQHFYKRGNIYPGNDTFDIDPE
IETECFFVEPDEPFHIGTPAENKLNLTLDFHRLLTVELQFKLKAINLQTVRHQELPDCYD
FTLTITFDNKAHSGRIKISLDNDISIRECKDWHVSGSIQKNTHYMMIFDAFVILTCLVSL
ILCIRSVIRGLQLQQEFVNFFLLHYKKEVSVSDQMEFVNGWYIMIIISDILTIIGSILKM
EIQAKSLTSYDVCSILLGTSTMLVWLGVIRYLGFFAKYNLLILTLQAALPNVIRFCCCAA
MIYLGYCFCGWIVLGPYHDKFRSLNMVSECLFSLINGDDMFATFAKMQQKSYLVWLFSRI
YLYSFISLFIYMILSLFIALITDTYETIKQYQQDGFPETELRTFISECKDLPNSGKYRLE
DDPPVSLFCCCKK

BDBM46838

n/a

Name

BDBM46838

Synonyms:

4-(2,5-dichlorophenyl)-N,N-dimethyl-1-piperazinesulfonamide | 4-(2,5-dichlorophenyl)-N,N-dimethyl-piperazine-1-sulfonamide | 4-(2,5-dichlorophenyl)-N,N-dimethylpiperazine-1-sulfonamide | 4-[2,5-bis(chloranyl)phenyl]-N,N-dimethyl-piperazine-1-sulfonamide | MLS000063673 | SMR000075372 | cid_849896

Type

Small organic molecule

Emp. Form.

C12H17Cl2N3O2S

Mol. Mass.

338.253

SMILES

CN(C)S(=O)(=O)N1CCN(CC1)c1cc(Cl)ccc1Cl

Structure