| Reaction Details |
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 | Report a problem with these data |
| Target | Mucolipin-3 |
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| Ligand | BDBM46846 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose response cell-based high-throughput screening assay for agonists of the transient receptor potential channel ML3 (TRPML3) |
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| EC50 | 8160±n/a nM |
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| Citation |  PubChem, PC Dose response cell-based high-throughput screening assay for agonists of the transient receptor potential channel ML3 (TRPML3) PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| Mucolipin-3 |
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| Name: | Mucolipin-3 |
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| Synonyms: | MCLN3_HUMAN | MCOLN3 | MCOLN3 protein |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 64244.09 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q8TDD5 |
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| Residue: | 553 |
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| Sequence: | MADPEVVVSSCSSHEEENRCNFNQQTSPSEELLLEDQMRRKLKFFFMNPCEKFWARGRKP
WKLAIQILKIAMVTIQLVLFGLSNQMVVAFKEENTIAFKHLFLKGYMDRMDDTYAVYTQS
DVYDQLIFAVNQYLQLYNVSVGNHAYENKGTKQSAMAICQHFYKRGNIYPGNDTFDIDPE
IETECFFVEPDEPFHIGTPAENKLNLTLDFHRLLTVELQFKLKAINLQTVRHQELPDCYD
FTLTITFDNKAHSGRIKISLDNDISIRECKDWHVSGSIQKNTHYMMIFDAFVILTCLVSL
ILCIRSVIRGLQLQQEFVNFFLLHYKKEVSVSDQMEFVNGWYIMIIISDILTIIGSILKM
EIQAKSLTSYDVCSILLGTSTMLVWLGVIRYLGFFAKYNLLILTLQAALPNVIRFCCCAA
MIYLGYCFCGWIVLGPYHDKFRSLNMVSECLFSLINGDDMFATFAKMQQKSYLVWLFSRI
YLYSFISLFIYMILSLFIALITDTYETIKQYQQDGFPETELRTFISECKDLPNSGKYRLE
DDPPVSLFCCCKK
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|
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| BDBM46846 |
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| n/a |
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| Name | BDBM46846 |
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| Synonyms: | 1-(5-chloranylthiophen-2-yl)sulfonyl-4-(2-ethoxyphenyl)piperazine | 1-(5-chlorothiophen-2-yl)sulfonyl-4-(2-ethoxyphenyl)piperazine | 1-[(5-chloro-2-thienyl)sulfonyl]-4-(2-ethoxyphenyl)piperazine | 1-[(5-chloro-2-thienyl)sulfonyl]-4-o-phenetyl-piperazine | 1-[(5-chloro-2-thiophenyl)sulfonyl]-4-(2-ethoxyphenyl)piperazine | MLS000062776 | SMR000073618 | cid_1314105 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H19ClN2O3S2 |
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| Mol. Mass. | 386.917 |
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| SMILES | CCOc1ccccc1N1CCN(CC1)S(=O)(=O)c1ccc(Cl)s1 |
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| Structure | 
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