| Reaction Details |
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 | Report a problem with these data |
| Target | Mucolipin-3 |
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| Ligand | BDBM46857 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose response cell-based high-throughput screening assay for agonists of the transient receptor potential channel ML3 (TRPML3) |
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| EC50 | 7220±n/a nM |
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| Citation |  PubChem, PC Dose response cell-based high-throughput screening assay for agonists of the transient receptor potential channel ML3 (TRPML3) PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| Mucolipin-3 |
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| Name: | Mucolipin-3 |
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| Synonyms: | MCLN3_HUMAN | MCOLN3 | MCOLN3 protein |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 64244.09 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q8TDD5 |
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| Residue: | 553 |
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| Sequence: | MADPEVVVSSCSSHEEENRCNFNQQTSPSEELLLEDQMRRKLKFFFMNPCEKFWARGRKP
WKLAIQILKIAMVTIQLVLFGLSNQMVVAFKEENTIAFKHLFLKGYMDRMDDTYAVYTQS
DVYDQLIFAVNQYLQLYNVSVGNHAYENKGTKQSAMAICQHFYKRGNIYPGNDTFDIDPE
IETECFFVEPDEPFHIGTPAENKLNLTLDFHRLLTVELQFKLKAINLQTVRHQELPDCYD
FTLTITFDNKAHSGRIKISLDNDISIRECKDWHVSGSIQKNTHYMMIFDAFVILTCLVSL
ILCIRSVIRGLQLQQEFVNFFLLHYKKEVSVSDQMEFVNGWYIMIIISDILTIIGSILKM
EIQAKSLTSYDVCSILLGTSTMLVWLGVIRYLGFFAKYNLLILTLQAALPNVIRFCCCAA
MIYLGYCFCGWIVLGPYHDKFRSLNMVSECLFSLINGDDMFATFAKMQQKSYLVWLFSRI
YLYSFISLFIYMILSLFIALITDTYETIKQYQQDGFPETELRTFISECKDLPNSGKYRLE
DDPPVSLFCCCKK
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| BDBM46857 |
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| n/a |
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| Name | BDBM46857 |
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| Synonyms: | 4,4-dimethyl-3-(4-methylphenyl)sulfonyl-1,3-thiazolidine-2-thione | 4,4-dimethyl-3-(4-methylphenyl)sulfonyl-2-thiazolidinethione | 4,4-dimethyl-3-tosyl-thiazolidine-2-thione | MLS000108476 | SMR000104433 | cid_792335 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H15NO2S3 |
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| Mol. Mass. | 301.448 |
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| SMILES | Cc1ccc(cc1)S(=O)(=O)N1C(=S)SCC1(C)C |
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| Structure | 
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