| Reaction Details |
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 | Report a problem with these data |
| Target | Mucolipin-3 |
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| Ligand | BDBM46858 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose response cell-based high-throughput screening assay for agonists of the transient receptor potential channel ML3 (TRPML3) |
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| EC50 | 2260±n/a nM |
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| Citation |  PubChem, PC Dose response cell-based high-throughput screening assay for agonists of the transient receptor potential channel ML3 (TRPML3) PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| Mucolipin-3 |
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| Name: | Mucolipin-3 |
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| Synonyms: | MCLN3_HUMAN | MCOLN3 | MCOLN3 protein |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 64244.09 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q8TDD5 |
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| Residue: | 553 |
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| Sequence: | MADPEVVVSSCSSHEEENRCNFNQQTSPSEELLLEDQMRRKLKFFFMNPCEKFWARGRKP
WKLAIQILKIAMVTIQLVLFGLSNQMVVAFKEENTIAFKHLFLKGYMDRMDDTYAVYTQS
DVYDQLIFAVNQYLQLYNVSVGNHAYENKGTKQSAMAICQHFYKRGNIYPGNDTFDIDPE
IETECFFVEPDEPFHIGTPAENKLNLTLDFHRLLTVELQFKLKAINLQTVRHQELPDCYD
FTLTITFDNKAHSGRIKISLDNDISIRECKDWHVSGSIQKNTHYMMIFDAFVILTCLVSL
ILCIRSVIRGLQLQQEFVNFFLLHYKKEVSVSDQMEFVNGWYIMIIISDILTIIGSILKM
EIQAKSLTSYDVCSILLGTSTMLVWLGVIRYLGFFAKYNLLILTLQAALPNVIRFCCCAA
MIYLGYCFCGWIVLGPYHDKFRSLNMVSECLFSLINGDDMFATFAKMQQKSYLVWLFSRI
YLYSFISLFIYMILSLFIALITDTYETIKQYQQDGFPETELRTFISECKDLPNSGKYRLE
DDPPVSLFCCCKK
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|
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| BDBM46858 |
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| n/a |
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| Name | BDBM46858 |
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| Synonyms: | 1-methyl-3,6-dihydro-2H-pyridine-5-carboxylic acid methyl ester;hydrobromide | ARECOLINE | ARECOLINE HYDROBROMIDE | MLS000028840 | SMR000058258 | arecoline;hydrobromide | cid_9301 | methyl 1-methyl-3,6-dihydro-2H-pyridine-5-carboxylate;hydrobromide |
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| Type | Small organic molecule |
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| Emp. Form. | C8H13NO2 |
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| Mol. Mass. | 155.1943 |
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| SMILES | COC(=O)C1=CCCN(C)C1 |t:4| |
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| Structure | 
|
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