| Reaction Details |
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 | Report a problem with these data |
| Target | Muscarinic acetylcholine receptor M3 |
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| Ligand | BDBM43819 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Discovery of novel allosteric modulators of the M1 muscarinic receptor: Agonist NMS competition at M3 |
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| EC50 | 76960±n/a nM |
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| Citation |  PubChem, PC Discovery of novel allosteric modulators of the M1 muscarinic receptor: Agonist NMS competition at M3 PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Muscarinic acetylcholine receptor M3 |
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| Name: | Muscarinic acetylcholine receptor M3 |
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| Synonyms: | ACM3_HUMAN | CHRM3 | Cholinergic, muscarinic M3 | Muscarinic Receptors M3 | Muscarinic receptor M3 | RecName: Full=Muscarinic acetylcholine receptor M3 |
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| Type: | Enzyme |
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| Mol. Mass.: | 66151.03 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P20309 |
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| Residue: | 590 |
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| Sequence: | MTLHNNSTTSPLFPNISSSWIHSPSDAGLPPGTVTHFGSYNVSRAAGNFSSPDGTTDDPL
GGHTVWQVVFIAFLTGILALVTIIGNILVIVSFKVNKQLKTVNNYFLLSLACADLIIGVI
SMNLFTTYIIMNRWALGNLACDLWLAIDYVASNASVMNLLVISFDRYFSITRPLTYRAKR
TTKRAGVMIGLAWVISFVLWAPAILFWQYFVGKRTVPPGECFIQFLSEPTITFGTAIAAF
YMPVTIMTILYWRIYKETEKRTKELAGLQASGTEAETENFVHPTGSSRSCSSYELQQQSM
KRSNRRKYGRCHFWFTTKSWKPSSEQMDQDHSSSDSWNNNDAAASLENSASSDEEDIGSE
TRAIYSIVLKLPGHSTILNSTKLPSSDNLQVPEEELGMVDLERKADKLQAQKSVDDGGSF
PKSFSKLPIQLESAVDTAKTSDVNSSVGKSTATLPLSFKEATLAKRFALKTRSQITKRKR
MSLVKEKKAAQTLSAILLAFIITWTPYNIMVLVNTFCDSCIPKTFWNLGYWLCYINSTVN
PVCYALCNKTFRTTFKMLLLCQCDKKKRRKQQYQQRQSVIFHKRAPEQAL
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| BDBM43819 |
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| n/a |
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| Name | BDBM43819 |
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| Synonyms: | 4-[2-(2-thenoylamino)ethylamino]piperidine-1-carboxylic acid ethyl ester | 4-[2-[[oxo(thiophen-2-yl)methyl]amino]ethylamino]-1-piperidinecarboxylic acid ethyl ester | 4-{2-[(Thiophene-2-carbonyl)-amino]-ethylamino}-piperidine-1-carboxylic acid ethyl ester | VU0177548 | cid_647412 | ethyl 4-[2-(thiophen-2-ylcarbonylamino)ethylamino]piperidine-1-carboxylate | ethyl 4-[2-(thiophene-2-carbonylamino)ethylamino]piperidine-1-carboxylate |
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| Type | Small organic molecule |
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| Emp. Form. | C15H23N3O3S |
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| Mol. Mass. | 325.426 |
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| SMILES | CCOC(=O)N1CCC(CC1)NCCNC(=O)c1cccs1 |
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| Structure | 
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