BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetGlutathione S-transferase Mu 1
LigandBDBM34465
Substrate/Competitorn/a
Meas. Tech.Profiling Assay to determine GST-GSH interactions in multiplex bead-based assays
EC50 4380±n/a nM
Citation PubChem, PC Profiling Assay to determine GST-GSH interactions in multiplex bead-based assays PubChem Bioassay(2010)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Glutathione S-transferase Mu 1
Name:Glutathione S-transferase Mu 1
Synonyms:GST class-mu 1 | GST1 | GSTM1 | GSTM1-1 | GSTM1_HUMAN | GSTM1a-1a | GSTM1b-1b | GTH4 | Glutathione S-transferase Mu 1 | HB subunit 4 | glutathione S-transferase
Type:PROTEIN
Mol. Mass.:25712.03
Organism:Homo sapiens (Human)
Description:ChEMBL_799596
Residue:218
Sequence:
MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL
PYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEF
EKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPN
LKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM34465
n/a
NameBDBM34465
Synonyms:2,5-dimethoxy-N-[4-oxidanyl-3-(1H-1,2,4-triazol-5-ylsulfanyl)phenyl]benzenesulfonamide | MLS000050072 | N-[4-hydroxy-3-(1H-1,2,4-triazol-3-ylthio)phenyl]-2,5-dimethoxybenzenesulfonamide | N-[4-hydroxy-3-(1H-1,2,4-triazol-5-ylsulfanyl)phenyl]-2,5-dimethoxybenzenesulfonamide | N-[4-hydroxy-3-(1H-1,2,4-triazol-5-ylthio)phenyl]-2,5-dimethoxy-benzenesulfonamide | N-[4-hydroxy-3-(1H-1,2,4-triazol-5-ylthio)phenyl]-2,5-dimethoxybenzenesulfonamide | SMR000077094 | cid_1589729
TypeSmall organic molecule
Emp. Form.C16H16N4O5S2
Mol. Mass.408.452
SMILESCOc1ccc(OC)c(c1)S(=O)(=O)Nc1ccc(O)c(Sc2nnc[nH]2)c1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: