Ki Summary

Reaction Details

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Target

Regulator of G-protein signaling 8

Ligand

BDBM47715

Substrate/Competitor

n/a

Meas. Tech.

Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao.

EC50

2290±n/a nM

Citation

PubChem, PC Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao. PubChem Bioassay(2009)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Regulator of G-protein signaling 8

Name:

Regulator of G-protein signaling 8

Synonyms:

RGS8 | RGS8_HUMAN | Regulator of G-protein signaling 8 (RGS8)

Type:

Enzyme Catalytic Domain

Mol. Mass.:

20925.80

Organism:

Homo sapiens (Human)

Description:

gi_74355113

Residue:

180

Sequence:

MAALLMPRRNKGMRTRLGCLSHKSDSCSDFTAILPDKPNRALKRLSTEEATRWADSFDVL
LSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPRE
VNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLLSQSQRRLS

BDBM47715

n/a

Name

BDBM47715

Synonyms:

DEFEROXAMINE | DEFEROXAMINE MESYLATE | MLS000028713 | N''-(5-azanylpentyl)-N-[5-[[4-[5-[ethanoyl(oxidanyl)amino]pentylamino]-4-oxidanylidene-butanoyl]-oxidanyl-amino]pentyl]-N''-oxidanyl-butanediamide;methanesulfonic acid | N-[5-[[4-[5-[acetyl(hydroxy)amino]pentylamino]-1,4-dioxobutyl]-hydroxyamino]pentyl]-N''-(5-aminopentyl)-N''-hydroxybutanediamide;methanesulfonic acid | N-[5-[[4-[5-[acetyl(hydroxy)amino]pentylamino]-4-keto-butanoyl]-hydroxy-amino]pentyl]-N'-(5-aminopentyl)-N'-hydroxy-succinamide;mesylic acid | N-[5-[[4-[5-[acetyl(hydroxy)amino]pentylamino]-4-oxobutanoyl]-hydroxyamino]pentyl]-N''-(5-aminopentyl)-N''-hydroxybutanediamide;methanesulfonic acid | SMR000058548 | cid_62881

Type

Small organic molecule

Emp. Form.

C25H48N6O8

Mol. Mass.

560.684

SMILES

CC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCN

Structure