Ki Summary

Reaction Details

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Target

Regulator of G-protein signaling 8

Ligand

BDBM47827

Substrate/Competitor

n/a

Meas. Tech.

Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao.

EC50

2050±n/a nM

Citation

PubChem, PC Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao. PubChem Bioassay(2009)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Regulator of G-protein signaling 8

Name:

Regulator of G-protein signaling 8

Synonyms:

RGS8 | RGS8_HUMAN | Regulator of G-protein signaling 8 (RGS8)

Type:

Enzyme Catalytic Domain

Mol. Mass.:

20925.80

Organism:

Homo sapiens (Human)

Description:

gi_74355113

Residue:

180

Sequence:

MAALLMPRRNKGMRTRLGCLSHKSDSCSDFTAILPDKPNRALKRLSTEEATRWADSFDVL
LSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPRE
VNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLLSQSQRRLS

BDBM47827

n/a

Name

BDBM47827

Synonyms:

1,12,23-trihydroxy-1,6,12,17,23,28-hexazacyclotritriacontane-2,5,13,16,24,27-hexone | 1,12,23-trihydroxy-1,6,12,17,23,28-hexazacyclotritriacontane-2,5,13,16,24,27-triquinone | 1,12,23-tris(oxidanyl)-1,6,12,17,23,28-hexazacyclotritriacontane-2,5,13,16,24,27-hexone | MLS000876815 | SMR000440583 | cid_161532

Type

Small organic molecule

Emp. Form.

C27H48N6O9

Mol. Mass.

600.7048

SMILES

ON1CCCCCNC(=O)CCC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCNC(=O)CCC1=O

Structure