Ki Summary

Reaction Details

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Target

Regulator of G-protein signaling 7

Ligand

BDBM41057

Substrate/Competitor

n/a

Meas. Tech.

Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS7-Galphao.

EC50

>30000±n/a nM

Citation

PubChem, PC Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS7-Galphao. PubChem Bioassay(2009)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Regulator of G-protein signaling 7

Name:

Regulator of G-protein signaling 7

Synonyms:

RGS7 | RGS7_HUMAN

Type:

Enzyme Catalytic Domain

Mol. Mass.:

57675.72

Organism:

Homo sapiens (Human)

Description:

P49802

Residue:

495

Sequence:

MAQGNNYGQTSNGVADESPNMLVYRKMEDVIARMQDEKNGIPIRTVKSFLSKIPSVFSGS
DIVQWLIKNLTIEDPVEALHLGTLMAAHGYFFPISDHVLTLKDDGTFYRFQTPYFWPSNC
WEPENTDYAVYLCKRTMQNKARLELADYEAESLARLQRAFARKWEFIFMQAEAQAKVDKK
RDKIERKILDSQERAFWDVHRPVPGCVNTTEVDIKKSSRMRNPHKTRKSVYGLQNDIRSH
SPTHTPTPETKPPTEDELQQQIKYWQIQLDRHRLKMSKVADSLLSYTEQYLEYDPFLLPP
DPSNPWLSDDTTFWELEASKEPSQQRVKRWGFGMDEALKDPVGREQFLKFLESEFSSENL
RFWLAVEDLKKRPIKEVPSRVQEIWQEFLAPGAPSAINLDSKSYDKTTQNVKEPGRYTFE
DAQEHIYKLMKSDSYPRFIRSSAYQELLQAKKKSGNSMDRRTSFEKFAQNVGRNIPIFPC
HKNCTPTLRASTNLL

BDBM41057

n/a

Name

BDBM41057

Synonyms:

MLS000544577 | N'-{2-(1-azepanyl)-5-nitrobenzylidene}-2-(9-oxo-10(9H)-acridinyl)acetohydrazide | N-[[2-(1-azepanyl)-5-nitrophenyl]methylideneamino]-2-(9-oxo-10-acridinyl)acetamide | N-[[2-(azepan-1-yl)-5-nitro-benzylidene]amino]-2-(9-ketoacridin-10-yl)acetamide | N-[[2-(azepan-1-yl)-5-nitro-phenyl]methylideneamino]-2-(9-oxidanylideneacridin-10-yl)ethanamide | N-[[2-(azepan-1-yl)-5-nitrophenyl]methylideneamino]-2-(9-oxoacridin-10-yl)acetamide | SMR000163144 | cid_2883648

Type

Small organic molecule

Emp. Form.

C28H27N5O4

Mol. Mass.

497.5451

SMILES

[O-][N+](=O)c1ccc(N2CCCCCC2)c([CH+][N-]NC(=O)Cn2c3ccccc3c(=O)c3ccccc23)c1

Structure