| Reaction Details |
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 | Report a problem with these data |
| Target | Regulator of G-protein signaling 7 |
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| Ligand | BDBM43064 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS7-Galphao. |
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| EC50 | >30000±n/a nM |
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| Citation |  PubChem, PC Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS7-Galphao. PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Regulator of G-protein signaling 7 |
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| Name: | Regulator of G-protein signaling 7 |
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| Synonyms: | RGS7 | RGS7_HUMAN |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 57675.72 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P49802 |
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| Residue: | 495 |
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| Sequence: | MAQGNNYGQTSNGVADESPNMLVYRKMEDVIARMQDEKNGIPIRTVKSFLSKIPSVFSGS
DIVQWLIKNLTIEDPVEALHLGTLMAAHGYFFPISDHVLTLKDDGTFYRFQTPYFWPSNC
WEPENTDYAVYLCKRTMQNKARLELADYEAESLARLQRAFARKWEFIFMQAEAQAKVDKK
RDKIERKILDSQERAFWDVHRPVPGCVNTTEVDIKKSSRMRNPHKTRKSVYGLQNDIRSH
SPTHTPTPETKPPTEDELQQQIKYWQIQLDRHRLKMSKVADSLLSYTEQYLEYDPFLLPP
DPSNPWLSDDTTFWELEASKEPSQQRVKRWGFGMDEALKDPVGREQFLKFLESEFSSENL
RFWLAVEDLKKRPIKEVPSRVQEIWQEFLAPGAPSAINLDSKSYDKTTQNVKEPGRYTFE
DAQEHIYKLMKSDSYPRFIRSSAYQELLQAKKKSGNSMDRRTSFEKFAQNVGRNIPIFPC
HKNCTPTLRASTNLL
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| BDBM43064 |
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| n/a |
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| Name | BDBM43064 |
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| Synonyms: | (5Z)-2-amino-5-[[3-(4-ethoxy-3-methyl-phenyl)-1-phenyl-pyrazol-4-yl]methylene]-2-thiazolin-4-one | (5Z)-2-amino-5-[[3-(4-ethoxy-3-methylphenyl)-1-phenyl-4-pyrazolyl]methylidene]-4-thiazolone | (5Z)-2-amino-5-[[3-(4-ethoxy-3-methylphenyl)-1-phenylpyrazol-4-yl]methylidene]-1,3-thiazol-4-one | (5Z)-2-azanyl-5-[[3-(4-ethoxy-3-methyl-phenyl)-1-phenyl-pyrazol-4-yl]methylidene]-1,3-thiazol-4-one | 5-{[3-(4-ethoxy-3-methylphenyl)-1-phenyl-1H-pyrazol-4-yl]methylene}-2-imino-1,3-thiazolidin-4-one | MLS000574241 | SMR000195833 | cid_1337412 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H20N4O2S |
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| Mol. Mass. | 404.485 |
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| SMILES | CCOc1ccc(cc1C)-c1nn(cc1C=C1SC(N)=NC1=O)-c1ccccc1 |w:15.16,c:21| |
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| Structure | 
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