Reaction Details |
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Target | Regulator of G-protein signaling 7 |
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Ligand | BDBM45025 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS7-Galphao. |
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EC50 | >30000±n/a nM |
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Citation | PubChem, PC Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS7-Galphao. PubChem Bioassay(2009)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Regulator of G-protein signaling 7 |
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Name: | Regulator of G-protein signaling 7 |
Synonyms: | RGS7 | RGS7_HUMAN |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 57675.72 |
Organism: | Homo sapiens (Human) |
Description: | P49802 |
Residue: | 495 |
Sequence: | MAQGNNYGQTSNGVADESPNMLVYRKMEDVIARMQDEKNGIPIRTVKSFLSKIPSVFSGS
DIVQWLIKNLTIEDPVEALHLGTLMAAHGYFFPISDHVLTLKDDGTFYRFQTPYFWPSNC
WEPENTDYAVYLCKRTMQNKARLELADYEAESLARLQRAFARKWEFIFMQAEAQAKVDKK
RDKIERKILDSQERAFWDVHRPVPGCVNTTEVDIKKSSRMRNPHKTRKSVYGLQNDIRSH
SPTHTPTPETKPPTEDELQQQIKYWQIQLDRHRLKMSKVADSLLSYTEQYLEYDPFLLPP
DPSNPWLSDDTTFWELEASKEPSQQRVKRWGFGMDEALKDPVGREQFLKFLESEFSSENL
RFWLAVEDLKKRPIKEVPSRVQEIWQEFLAPGAPSAINLDSKSYDKTTQNVKEPGRYTFE
DAQEHIYKLMKSDSYPRFIRSSAYQELLQAKKKSGNSMDRRTSFEKFAQNVGRNIPIFPC
HKNCTPTLRASTNLL
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BDBM45025 |
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n/a |
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Name | BDBM45025 |
Synonyms: | 1,6,6-triphenyl-3-(p-tolyl)-3-azabicyclo[3.1.0]hexane-2,4-quinone | 3-(4-methylphenyl)-1,6,6-triphenyl-3-azabicyclo[3.1.0]hexane-2,4-dione | MLS000577352 | SMR000197462 | cid_2929373 |
Type | Small organic molecule |
Emp. Form. | C30H23NO2 |
Mol. Mass. | 429.5091 |
SMILES | Cc1ccc(cc1)N1C(=O)C2C(C1=O)(c1ccccc1)C2(c1ccccc1)c1ccccc1 |
Structure |
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