| Reaction Details |
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 | Report a problem with these data |
| Target | Regulator of G-protein signaling 7 |
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| Ligand | BDBM47733 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS7-Galphao. |
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| EC50 | >30000±n/a nM |
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| Citation |  PubChem, PC Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS7-Galphao. PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Regulator of G-protein signaling 7 |
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| Name: | Regulator of G-protein signaling 7 |
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| Synonyms: | RGS7 | RGS7_HUMAN |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 57675.72 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P49802 |
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| Residue: | 495 |
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| Sequence: | MAQGNNYGQTSNGVADESPNMLVYRKMEDVIARMQDEKNGIPIRTVKSFLSKIPSVFSGS
DIVQWLIKNLTIEDPVEALHLGTLMAAHGYFFPISDHVLTLKDDGTFYRFQTPYFWPSNC
WEPENTDYAVYLCKRTMQNKARLELADYEAESLARLQRAFARKWEFIFMQAEAQAKVDKK
RDKIERKILDSQERAFWDVHRPVPGCVNTTEVDIKKSSRMRNPHKTRKSVYGLQNDIRSH
SPTHTPTPETKPPTEDELQQQIKYWQIQLDRHRLKMSKVADSLLSYTEQYLEYDPFLLPP
DPSNPWLSDDTTFWELEASKEPSQQRVKRWGFGMDEALKDPVGREQFLKFLESEFSSENL
RFWLAVEDLKKRPIKEVPSRVQEIWQEFLAPGAPSAINLDSKSYDKTTQNVKEPGRYTFE
DAQEHIYKLMKSDSYPRFIRSSAYQELLQAKKKSGNSMDRRTSFEKFAQNVGRNIPIFPC
HKNCTPTLRASTNLL
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| BDBM47733 |
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| n/a |
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| Name | BDBM47733 |
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| Synonyms: | 4-(5-Phenoxymethyl-4-phenyl-4H-[1,2,4]triazol-3-ylsulfanylmethyl)-1H-quinolin-2-one | 4-[[5-(phenoxymethyl)-4-phenyl-1,2,4-triazol-3-yl]sulfanylmethyl]-1H-quinolin-2-one | 4-[[[5-(phenoxymethyl)-4-phenyl-1,2,4-triazol-3-yl]thio]methyl]-1H-quinolin-2-one | 4-[[[5-(phenoxymethyl)-4-phenyl-1,2,4-triazol-3-yl]thio]methyl]carbostyril | MLS000547635 | SMR000172128 | cid_1134963 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H20N4O2S |
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| Mol. Mass. | 440.517 |
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| SMILES | O=c1cc(CSc2nnc(COc3ccccc3)n2-c2ccccc2)c2ccccc2[nH]1 |
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| Structure | 
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