| Reaction Details |
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 | Report a problem with these data |
| Target | Regulator of G-protein signaling 7 |
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| Ligand | BDBM47786 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS7-Galphao. |
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| EC50 | >30000±n/a nM |
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| Citation |  PubChem, PC Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS7-Galphao. PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Regulator of G-protein signaling 7 |
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| Name: | Regulator of G-protein signaling 7 |
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| Synonyms: | RGS7 | RGS7_HUMAN |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 57675.72 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P49802 |
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| Residue: | 495 |
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| Sequence: | MAQGNNYGQTSNGVADESPNMLVYRKMEDVIARMQDEKNGIPIRTVKSFLSKIPSVFSGS
DIVQWLIKNLTIEDPVEALHLGTLMAAHGYFFPISDHVLTLKDDGTFYRFQTPYFWPSNC
WEPENTDYAVYLCKRTMQNKARLELADYEAESLARLQRAFARKWEFIFMQAEAQAKVDKK
RDKIERKILDSQERAFWDVHRPVPGCVNTTEVDIKKSSRMRNPHKTRKSVYGLQNDIRSH
SPTHTPTPETKPPTEDELQQQIKYWQIQLDRHRLKMSKVADSLLSYTEQYLEYDPFLLPP
DPSNPWLSDDTTFWELEASKEPSQQRVKRWGFGMDEALKDPVGREQFLKFLESEFSSENL
RFWLAVEDLKKRPIKEVPSRVQEIWQEFLAPGAPSAINLDSKSYDKTTQNVKEPGRYTFE
DAQEHIYKLMKSDSYPRFIRSSAYQELLQAKKKSGNSMDRRTSFEKFAQNVGRNIPIFPC
HKNCTPTLRASTNLL
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| BDBM47786 |
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| n/a |
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| Name | BDBM47786 |
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| Synonyms: | 6-chloro-3-pyridinecarboxylic acid [2-(tert-butylamino)-2-oxoethyl] ester | 6-chloronicotinic acid [2-(tert-butylamino)-2-keto-ethyl] ester | MLS000709523 | SMR000286890 | [2-(tert-butylamino)-2-oxidanylidene-ethyl] 6-chloranylpyridine-3-carboxylate | [2-(tert-butylamino)-2-oxoethyl] 6-chloropyridine-3-carboxylate | cid_2432404 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H15ClN2O3 |
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| Mol. Mass. | 270.712 |
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| SMILES | CC(C)(C)NC(=O)COC(=O)c1ccc(Cl)nc1 |
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| Structure | 
|
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