Ki Summary

Reaction Details

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Target

Regulator of G-protein signaling 19

Ligand

BDBM47704

Substrate/Competitor

n/a

Meas. Tech.

Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS19-Galphao.

EC50

>30000±n/a nM

Citation

PubChem, PC Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS19-Galphao. PubChem Bioassay(2009)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Regulator of G-protein signaling 19

Name:

Regulator of G-protein signaling 19

Synonyms:

Type:

Enzyme Catalytic Domain

Mol. Mass.:

24631.38

Organism:

Homo sapiens (Human)

Description:

gi_86990435

Residue:

217

Sequence:

MPTPHEAEKQITGPEEADRPPSMSSHDTASPAAPSRNPCCLCWCCCCSCSWNQERRRAWQ
ASRESKLQPLPSCEVCATPSPEEVQSWAQSFDKLMHSPAGRSVFRAFLRTEYSEENMLFW
LACEELKAEANQHVVDEKARLIYEDYVSILSPKEVSLDSRVREGINKKMQEPSAHTFDDA
QLQIYTLMHRDSYPRFLSSPTYRALLLQGPSQSSSEA

BDBM47704

n/a

Name

BDBM47704

Synonyms:

2-[[3-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-4-keto-quinazolin-2-yl]thio]acetic acid ethyl ester | 2-[[3-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-4-oxo-2-quinazolinyl]thio]acetic acid ethyl ester | MLS000095253 | SMR000030807 | cid_3240424 | ethyl 2-[3-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-4-oxidanylidene-quinazolin-2-yl]sulfanylethanoate | ethyl 2-[3-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-4-oxoquinazolin-2-yl]sulfanylacetate | ethyl {[3-(2,3-dihydro-1,4-benzodioxin-2-ylmethyl)-4-oxo-3,4-dihydroquinazolin-2-yl]thio}acetate

Type

Small organic molecule

Emp. Form.

C21H20N2O5S

Mol. Mass.

412.459

SMILES

CCOC(=O)CSc1nc2ccccc2c(=O)n1CC1COc2ccccc2O1

Structure