Ki Summary

Reaction Details

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Target

Regulator of G-protein signaling 19

Ligand

BDBM47723

Substrate/Competitor

n/a

Meas. Tech.

Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS19-Galphao.

EC50

>30000±n/a nM

Citation

PubChem, PC Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS19-Galphao. PubChem Bioassay(2009)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Regulator of G-protein signaling 19

Name:

Regulator of G-protein signaling 19

Synonyms:

Type:

Enzyme Catalytic Domain

Mol. Mass.:

24631.38

Organism:

Homo sapiens (Human)

Description:

gi_86990435

Residue:

217

Sequence:

MPTPHEAEKQITGPEEADRPPSMSSHDTASPAAPSRNPCCLCWCCCCSCSWNQERRRAWQ
ASRESKLQPLPSCEVCATPSPEEVQSWAQSFDKLMHSPAGRSVFRAFLRTEYSEENMLFW
LACEELKAEANQHVVDEKARLIYEDYVSILSPKEVSLDSRVREGINKKMQEPSAHTFDDA
QLQIYTLMHRDSYPRFLSSPTYRALLLQGPSQSSSEA

BDBM47723

n/a

Name

BDBM47723

Synonyms:

(5Z)-1-(2-furanylmethyl)-2-sulfanylidene-5-[(thiophen-2-ylmethylamino)methylidene]-1,3-diazinane-4,6-dione | (5Z)-1-(2-furfuryl)-5-[(2-thenylamino)methylene]-2-thioxo-hexahydropyrimidine-4,6-quinone | (5Z)-1-(furan-2-ylmethyl)-2-sulfanylidene-5-[(thiophen-2-ylmethylamino)methylidene]-1,3-diazinane-4,6-dione | 1-(2-furylmethyl)-5-{[(2-thienylmethyl)amino]methylene}-2-thioxodihydro-4,6(1H,5H)-pyrimidinedione | MLS000535170 | SMR000142606 | cid_5415835

Type

Small organic molecule

Emp. Form.

C15H13N3O3S2

Mol. Mass.

347.412

SMILES

O=C1NC(=S)N(Cc2ccco2)C(=O)C1=CNCc1cccs1 |w:15.17|

Structure