Reaction Details |
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Target | Regulator of G-protein signaling 19 |
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Ligand | BDBM47723 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS19-Galphao. |
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EC50 | >30000±n/a nM |
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Citation | PubChem, PC Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS19-Galphao. PubChem Bioassay(2009)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Regulator of G-protein signaling 19 |
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Name: | Regulator of G-protein signaling 19 |
Synonyms: | G protein signalling regulator 19 | GAIP | GNAI3IP | RGS19 | RGS19_HUMAN | Regulator of G-protein signaling 19 (RGS19) |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 24631.38 |
Organism: | Homo sapiens (Human) |
Description: | gi_86990435 |
Residue: | 217 |
Sequence: | MPTPHEAEKQITGPEEADRPPSMSSHDTASPAAPSRNPCCLCWCCCCSCSWNQERRRAWQ
ASRESKLQPLPSCEVCATPSPEEVQSWAQSFDKLMHSPAGRSVFRAFLRTEYSEENMLFW
LACEELKAEANQHVVDEKARLIYEDYVSILSPKEVSLDSRVREGINKKMQEPSAHTFDDA
QLQIYTLMHRDSYPRFLSSPTYRALLLQGPSQSSSEA
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BDBM47723 |
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n/a |
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Name | BDBM47723 |
Synonyms: | (5Z)-1-(2-furanylmethyl)-2-sulfanylidene-5-[(thiophen-2-ylmethylamino)methylidene]-1,3-diazinane-4,6-dione | (5Z)-1-(2-furfuryl)-5-[(2-thenylamino)methylene]-2-thioxo-hexahydropyrimidine-4,6-quinone | (5Z)-1-(furan-2-ylmethyl)-2-sulfanylidene-5-[(thiophen-2-ylmethylamino)methylidene]-1,3-diazinane-4,6-dione | 1-(2-furylmethyl)-5-{[(2-thienylmethyl)amino]methylene}-2-thioxodihydro-4,6(1H,5H)-pyrimidinedione | MLS000535170 | SMR000142606 | cid_5415835 |
Type | Small organic molecule |
Emp. Form. | C15H13N3O3S2 |
Mol. Mass. | 347.412 |
SMILES | O=C1NC(=S)N(Cc2ccco2)C(=O)C1=CNCc1cccs1 |w:15.17| |
Structure |
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