Reaction Details |
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Target | Regulator of G-protein signaling 19 |
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Ligand | BDBM47790 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS19-Galphao. |
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EC50 | 1240±n/a nM |
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Citation | PubChem, PC Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS19-Galphao. PubChem Bioassay(2009)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Regulator of G-protein signaling 19 |
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Name: | Regulator of G-protein signaling 19 |
Synonyms: | G protein signalling regulator 19 | GAIP | GNAI3IP | RGS19 | RGS19_HUMAN | Regulator of G-protein signaling 19 (RGS19) |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 24631.38 |
Organism: | Homo sapiens (Human) |
Description: | gi_86990435 |
Residue: | 217 |
Sequence: | MPTPHEAEKQITGPEEADRPPSMSSHDTASPAAPSRNPCCLCWCCCCSCSWNQERRRAWQ
ASRESKLQPLPSCEVCATPSPEEVQSWAQSFDKLMHSPAGRSVFRAFLRTEYSEENMLFW
LACEELKAEANQHVVDEKARLIYEDYVSILSPKEVSLDSRVREGINKKMQEPSAHTFDDA
QLQIYTLMHRDSYPRFLSSPTYRALLLQGPSQSSSEA
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BDBM47790 |
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n/a |
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Name | BDBM47790 |
Synonyms: | 2-(4,6-dimethyl-3-oxidanylidene-[1,2]thiazolo[5,4-b]pyridin-2-yl)-N-(3-fluorophenyl)ethanamide | 2-(4,6-dimethyl-3-oxo-2-isothiazolo[5,4-b]pyridinyl)-N-(3-fluorophenyl)acetamide | 2-(4,6-dimethyl-3-oxo-[1,2]thiazolo[5,4-b]pyridin-2-yl)-N-(3-fluorophenyl)acetamide | 2-(4,6-dimethyl-3-oxoisothiazolo[5,4-b]pyridin-2(3H)-yl)-N-(3-fluorophenyl)acetamide | MLS000689392 | N-(3-fluorophenyl)-2-(3-keto-4,6-dimethyl-isothiazolo[5,4-b]pyridin-2-yl)acetamide | SMR000311191 | cid_4247468 |
Type | Small organic molecule |
Emp. Form. | C16H14FN3O2S |
Mol. Mass. | 331.365 |
SMILES | Cc1cc(C)c2c(n1)sn(CC(=O)Nc1cccc(F)c1)c2=O |
Structure |
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