Ki Summary

Reaction Details

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Target

Regulator of G-protein signaling 16

Ligand

BDBM47782

Substrate/Competitor

n/a

Meas. Tech.

Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao.

EC50

>30000±n/a nM

Citation

PubChem, PC Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao. PubChem Bioassay(2009)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Regulator of G-protein signaling 16

Name:

Regulator of G-protein signaling 16

Synonyms:

RGS16 | RGS16_HUMAN | RGSR | Regulator of G-protein signaling 16 (RGS16) | regulator of G-protein signalling 16

Type:

Enzyme Catalytic Domain

Mol. Mass.:

22748.87

Organism:

Homo sapiens (Human)

Description:

gi_156416009

Residue:

202

Sequence:

MCRTLAAFPTTCLERAKEFKTRLGIFLHKSELGCDTGSTGKFEWGSKHSKENRNFSEDVL
GWRESFDLLLSSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLASRAHQIFEE
FICSEAPKEVNIDHETHELTRMNLQTATATCFDAAQGKTRTLMEKDSYPRFLKSPAYRDL
AAQASAASATLSSCSLDEPSHT

BDBM47782

n/a

Name

BDBM47782

Synonyms:

4-(2-methoxyphenyl)-3-phenyl-1H-1,2,4-triazole-5-thione | MLS000689122 | SMR000283119 | cid_863515

Type

Small organic molecule

Emp. Form.

C15H13N3OS

Mol. Mass.

283.348

SMILES

COc1ccccc1-n1c(n[nH]c1=S)-c1ccccc1 |(3.08,-1.57,;4.41,-.8,;5.75,-1.57,;5.75,-3.11,;7.08,-3.88,;8.41,-3.11,;8.41,-1.57,;7.08,-.8,;7.08,.74,;8.33,1.64,;7.85,3.11,;6.31,3.11,;5.84,1.64,;4.37,1.17,;9.79,1.17,;10.11,-.34,;11.58,-.81,;12.72,.22,;12.4,1.72,;10.94,2.2,)|

Structure