| Reaction Details |
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 | Report a problem with these data |
| Target | Regulator of G-protein signaling 16 |
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| Ligand | BDBM47788 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao. |
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| EC50 | >30000±n/a nM |
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| Citation |  PubChem, PC Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao. PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| Regulator of G-protein signaling 16 |
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| Name: | Regulator of G-protein signaling 16 |
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| Synonyms: | RGS16 | RGS16_HUMAN | RGSR | Regulator of G-protein signaling 16 (RGS16) | regulator of G-protein signalling 16 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 22748.87 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_156416009 |
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| Residue: | 202 |
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| Sequence: | MCRTLAAFPTTCLERAKEFKTRLGIFLHKSELGCDTGSTGKFEWGSKHSKENRNFSEDVL
GWRESFDLLLSSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLASRAHQIFEE
FICSEAPKEVNIDHETHELTRMNLQTATATCFDAAQGKTRTLMEKDSYPRFLKSPAYRDL
AAQASAASATLSSCSLDEPSHT
|
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|
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| BDBM47788 |
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| n/a |
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| Name | BDBM47788 |
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| Synonyms: | MLS000693599 | SMR000285488 | [3-cyclohexyl-5-hydroxy-5-(trifluoromethyl)-2-pyrazolin-1-yl]-(4-pyridyl)methanone | [3-cyclohexyl-5-hydroxy-5-(trifluoromethyl)-4H-pyrazol-1-yl]-pyridin-4-ylmethanone | [3-cyclohexyl-5-oxidanyl-5-(trifluoromethyl)-4H-pyrazol-1-yl]-pyridin-4-yl-methanone | cid_2881606 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H18F3N3O2 |
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| Mol. Mass. | 341.3282 |
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| SMILES | OC1(CC(=NN1C(=O)c1ccncc1)C1CCCCC1)C(F)(F)F |c:3| |
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| Structure | 
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