| Reaction Details |
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 | Report a problem with these data |
| Target | Regulator of G-protein signaling 16 |
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| Ligand | BDBM47791 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao. |
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| EC50 | 1750±n/a nM |
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| Citation |  PubChem, PC Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao. PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| Regulator of G-protein signaling 16 |
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| Name: | Regulator of G-protein signaling 16 |
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| Synonyms: | RGS16 | RGS16_HUMAN | RGSR | Regulator of G-protein signaling 16 (RGS16) | regulator of G-protein signalling 16 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 22748.87 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_156416009 |
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| Residue: | 202 |
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| Sequence: | MCRTLAAFPTTCLERAKEFKTRLGIFLHKSELGCDTGSTGKFEWGSKHSKENRNFSEDVL
GWRESFDLLLSSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLASRAHQIFEE
FICSEAPKEVNIDHETHELTRMNLQTATATCFDAAQGKTRTLMEKDSYPRFLKSPAYRDL
AAQASAASATLSSCSLDEPSHT
|
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|
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| BDBM47791 |
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| n/a |
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| Name | BDBM47791 |
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| Synonyms: | 2-(3-keto-4,6-dimethyl-isothiazolo[5,4-b]pyridin-2-yl)-N-propyl-acetamide | 2-(4,6-dimethyl-3-oxidanylidene-[1,2]thiazolo[5,4-b]pyridin-2-yl)-N-propyl-ethanamide | 2-(4,6-dimethyl-3-oxo-2-isothiazolo[5,4-b]pyridinyl)-N-propylacetamide | 2-(4,6-dimethyl-3-oxo-[1,2]thiazolo[5,4-b]pyridin-2-yl)-N-propylacetamide | 2-(4,6-dimethyl-3-oxoisothiazolo[5,4-b]pyridin-2(3H)-yl)-N-propylacetamide | MLS000731514 | SMR000309789 | cid_6619971 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H17N3O2S |
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| Mol. Mass. | 279.358 |
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| SMILES | CCCNC(=O)Cn1sc2nc(C)cc(C)c2c1=O |
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| Structure | 
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