| Reaction Details |
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 | Report a problem with these data |
| Target | Estrogen receptor beta |
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| Ligand | BDBM48375 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Estrogen Receptor-beta Coactivator Binding Inhibitors Dose Response Confirmation |
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| IC50 | 50000±n/a nM |
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| Citation |  PubChem, PC Estrogen Receptor-beta Coactivator Binding Inhibitors Dose Response Confirmation PubChem Bioassay(2007)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Estrogen receptor beta |
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| Name: | Estrogen receptor beta |
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| Synonyms: | ER-beta | ESR2 | ESR2_HUMAN | ESTRB | Estradiol receptor beta (ERβ) | Estrogen receptor | Estrogen receptor (ER beta) | Estrogen receptor beta | Estrogen receptor beta (ER beta) | Estrogen receptor beta (ER) | NR3A2 | Nuclear receptor subfamily 3 group A member 2 | estrogen beta |
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| Type: | Protein |
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| Mol. Mass.: | 59238.43 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q92731 |
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| Residue: | 530 |
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| Sequence: | MDIKNSPSSLNSPSSYNCSQSILPLEHGSIYIPSSYVDSHHEYPAMTFYSPAVMNYSIPS
NVTNLEGGPGRQTTSPNVLWPTPGHLSPLVVHRQLSHLYAEPQKSPWCEARSLEHTLPVN
RETLKRKVSGNRCASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGH
NDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLH
CAGKAKRSGGHAPRVRELLLDALSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTK
LADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDL
VLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDA
DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMK
CKNVVPVYDLLLEMLNAHVLRGCKSSITGSECSPAEDSKSKEGSQNPQSQ
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| BDBM48375 |
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| n/a |
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| Name | BDBM48375 |
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| Synonyms: | MLS000096473 | N-(3-cyano-2-thienyl)-2-(quinazolin-4-ylthio)acetamide | N-(3-cyano-2-thiophenyl)-2-(4-quinazolinylthio)acetamide | N-(3-cyanothiophen-2-yl)-2-quinazolin-4-ylsulfanyl-ethanamide | N-(3-cyanothiophen-2-yl)-2-quinazolin-4-ylsulfanylacetamide | SMR000062024 | cid_2369720 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H10N4OS2 |
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| Mol. Mass. | 326.396 |
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| SMILES | O=C(CSc1ncnc2ccccc12)Nc1sccc1C#N |
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| Structure | 
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