Reaction Details |
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Target | Transcription factor p65 |
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Ligand | BDBM49423 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Name: High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Dose Response |
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EC50 | 6873±n/a nM |
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Citation | PubChem, PC Name: High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Dose Response PubChem Bioassay(2008)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Transcription factor p65 |
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Name: | Transcription factor p65 |
Synonyms: | NFKB3 | Nuclear factor NF-kappa-B | Nuclear factor NF-kappa-B p65 subunit | RELA | TF65_HUMAN | v-rel reticuloendotheliosis viral oncogene homolog A isoform 1 |
Type: | Enzyme |
Mol. Mass.: | 60211.92 |
Organism: | Homo sapiens (Human) |
Description: | Q04206 |
Residue: | 551 |
Sequence: | MDELFPLIFPAEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPT
IKINGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGFYEAELCPDRCIHSFQNLGIQC
VKKRDLEQAISQRIQTNNNPFQVPIEEQRGDYDLNAVRLCFQVTVRDPSGRPLRLPPVLS
HPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPGWEARGSFS
QADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRHRIEE
KRKRTYETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINY
DEFPTMVFPSGQISQASALAPAPPQVLPQAPAPAPAPAMVSALAQAPAPVPVLAPGPPQA
VAPPAPKPTQAGEGTLSEALLQLQFDDEDLGALLGNSTDPAVFTDLASVDNSEFQQLLNQ
GIPVAPHTTEPMLMEYPEAITRLVTGAQRPPDPAPAPLGAPGLPNGLLSGDEDFSSIADM
DFSALLSQISS
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BDBM49423 |
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n/a |
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Name | BDBM49423 |
Synonyms: | (E)-3-(3,4-dimethylanilino)-2-(3-thienyl)acrylonitrile | (E)-3-(3,4-dimethylanilino)-2-(3-thiophenyl)-2-propenenitrile | (E)-3-(3,4-dimethylanilino)-2-thiophen-3-ylprop-2-enenitrile | (E)-3-[(3,4-dimethylphenyl)amino]-2-thiophen-3-yl-prop-2-enenitrile | MLS000539447 | SMR000125105 | cid_2766393 |
Type | Small organic molecule |
Emp. Form. | C15H14N2S |
Mol. Mass. | 254.35 |
SMILES | Cc1ccc(cc1C)N=CC(C#N)c1ccsc1 |w:8.8| |
Structure |
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