Reaction Details |
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Target | Transcription factor p65 |
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Ligand | BDBM49951 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Name: High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Dose Response |
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EC50 | 4142±n/a nM |
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Citation | PubChem, PC Name: High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Dose Response PubChem Bioassay(2008)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Transcription factor p65 |
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Name: | Transcription factor p65 |
Synonyms: | NFKB3 | Nuclear factor NF-kappa-B | Nuclear factor NF-kappa-B p65 subunit | RELA | TF65_HUMAN | v-rel reticuloendotheliosis viral oncogene homolog A isoform 1 |
Type: | Enzyme |
Mol. Mass.: | 60211.92 |
Organism: | Homo sapiens (Human) |
Description: | Q04206 |
Residue: | 551 |
Sequence: | MDELFPLIFPAEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPT
IKINGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGFYEAELCPDRCIHSFQNLGIQC
VKKRDLEQAISQRIQTNNNPFQVPIEEQRGDYDLNAVRLCFQVTVRDPSGRPLRLPPVLS
HPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPGWEARGSFS
QADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRHRIEE
KRKRTYETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINY
DEFPTMVFPSGQISQASALAPAPPQVLPQAPAPAPAPAMVSALAQAPAPVPVLAPGPPQA
VAPPAPKPTQAGEGTLSEALLQLQFDDEDLGALLGNSTDPAVFTDLASVDNSEFQQLLNQ
GIPVAPHTTEPMLMEYPEAITRLVTGAQRPPDPAPAPLGAPGLPNGLLSGDEDFSSIADM
DFSALLSQISS
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BDBM49951 |
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n/a |
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Name | BDBM49951 |
Synonyms: | MLS001010697 | N-[2-[(5Z)-2,4-diketo-5-p-anisylidene-thiazolidin-3-yl]ethyl]bicyclo[2.2.1]hept-2-ene-5-carboxamide | N-[2-[(5Z)-5-[(4-methoxyphenyl)methylidene]-2,4-bis(oxidanylidene)-1,3-thiazolidin-3-yl]ethyl]bicyclo[2.2.1]hept-2-ene-5-carboxamide | N-[2-[(5Z)-5-[(4-methoxyphenyl)methylidene]-2,4-dioxo-1,3-thiazolidin-3-yl]ethyl]bicyclo[2.2.1]hept-2-ene-5-carboxamide | N-[2-[(5Z)-5-[(4-methoxyphenyl)methylidene]-2,4-dioxo-3-thiazolidinyl]ethyl]-5-bicyclo[2.2.1]hept-2-enecarboxamide | SMR000352864 | cid_5969645 |
Type | Small organic molecule |
Emp. Form. | C21H22N2O4S |
Mol. Mass. | 398.475 |
SMILES | [H]C12CC(C(=O)NCCN3C(=O)S\C(=C/c4ccc(OC)cc4)C3=O)C([H])(C1)C=C2 |c:31,THB:4:3:27:28.29| |
Structure |
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