Reaction Details |
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Target | Induced myeloid leukemia cell differentiation protein Mcl-1 |
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Ligand | BDBM50104 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Dose Response Confirmation for Mcl-1/Noxa Interaction Inhibitors |
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IC50 | 400±n/a nM |
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Citation | PubChem, PC Dose Response Confirmation for Mcl-1/Noxa Interaction Inhibitors PubChem Bioassay(2008)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Induced myeloid leukemia cell differentiation protein Mcl-1 |
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Name: | Induced myeloid leukemia cell differentiation protein Mcl-1 |
Synonyms: | BCL2L3 | Bcl-2-like protein 3 | Bcl-2-like protein 3 (Mcl-1) | Bcl-2-related protein EAT/mcl1 | Bcl2-L-3 | Induced myeloid leukemia cell differentiation protein (Mcl-1) | MCL1 | MCL1_HUMAN | Mcl-1 | Myeloid Cell factor-1 (Mcl-1) | Myeloid cell leukemia sequence 1 (BCL2-related) | mcl1/EAT |
Type: | Membrane; Single-pass membrane protein |
Mol. Mass.: | 37332.87 |
Organism: | Homo sapiens (Human) |
Description: | Q07820 |
Residue: | 350 |
Sequence: | MFGLKRNAVIGLNLYCGGAGLGAGSGGATRPGGRLLATEKEASARREIGGGEAGAVIGGS
AGASPPSTLTPDSRRVARPPPIGAEVPDVTATPARLLFFAPTRRAAPLEEMEAPAADAIM
SPEEELDGYEPEPLGKRPAVLPLLELVGESGNNTSTDGSLPSTPPPAEEEEDELYRQSLE
IISRYLREQATGAKDTKPMGRSGATSRKALETLRRVGDGVQRNHETAFQGMLRKLDIKNE
DDVKSLSRVMIHVFSDGVTNWGRIVTLISFGAFVAKHLKTINQESCIEPLAESITDVLVR
TKRDWLVKQRGWDGFVEFFHVEDLEGGIRNVLLAFAGVAGVGAGLAYLIR
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BDBM50104 |
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n/a |
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Name | BDBM50104 |
Synonyms: | 3-[2-[[5-(4-nitrophenyl)-2-furanyl]methylidene]hydrazinyl]-2-indolone | 3-[2-[[5-(4-nitrophenyl)furan-2-yl]methylidene]hydrazinyl]indol-2-one | 3-[N'-[[5-(4-nitrophenyl)-2-furyl]methylene]hydrazino]indol-2-one | 5-{4-nitrophenyl}-2-furaldehyde (2-oxo-1,2-dihydro-3H-indol-3-ylidene)hydrazone | MLS000548221 | SMR000114874 | cid_1224795 |
Type | Small organic molecule |
Emp. Form. | C19H12N4O4 |
Mol. Mass. | 360.323 |
SMILES | [O-][N+](=O)c1ccc(cc1)-c1ccc([CH+]\N=[NH+]\[c-]2c3ccccc3[n-]c2=O)o1 |
Structure |
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