Search and Browse
Download
Enter Data
| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | E3 ubiquitin-protein ligase Mdm2 | ||
| Ligand | BDBM43484 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | E3 Ligase_Mutant_Dose Response | ||
| EC50 | 1110±n/a nM | ||
| Citation |  PubChem, PC E3 Ligase_Mutant_Dose Response PubChem Bioassay(2008)[AID] | ||
| More Info.: | Get all data from this article, Solution Info, Assay Method | ||
| E3 ubiquitin-protein ligase Mdm2 | |||
| Name: | E3 ubiquitin-protein ligase Mdm2 | ||
| Synonyms: | Double minute 2 protein | Double minute 2 protein (HDM2) | E3 ubiquitin-protein ligase Mdm2 (p53-binding protein Mdm2) | Hdm2 | Human Double Minute 2 (HDM2) | MDM2 | MDM2-MDMX | MDM2_HUMAN | p53-Binding Protein MDM2 | p53-binding protein | ||
| Type: | Oncoprotein | ||
| Mol. Mass.: | 55196.54 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q00987 | ||
| Residue: | 491 | ||
| Sequence: |
| ||
| BDBM43484 | |||
| n/a | |||
| Name | BDBM43484 | ||
| Synonyms: | (3aR,5R,5aR,8aR,9S,9aS)-5,8a-dimethyl-1-methylidene-9-oxidanyl-3a,4,5,5a,9,9a-hexahydroazuleno[6,7-b]furan-2,8-dione | (3aR,5R,5aR,8aR,9S,9aS)-9-hydroxy-5,8a-dimethyl-1-methylene-3a,4,5,5a,9,9a-hexahydroazuleno[6,7-b]furan-2,8-dione | (3aR,5R,5aR,8aR,9S,9aS)-9-hydroxy-5,8a-dimethyl-1-methylene-3a,4,5,5a,9,9a-hexahydroazuleno[6,7-b]furan-2,8-quinone | (3aR,5R,5aR,8aR,9S,9aS)-9-hydroxy-5,8a-dimethyl-1-methylidene-3a,4,5,5a,9,9a-hexahydroazuleno[6,7-b]furan-2,8-dione | Helenalin | MLS000728512 | SMR000445626 | cid_23205 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C15H18O4 | ||
| Mol. Mass. | 262.301 | ||
| SMILES | C[C@@H]1C[C@H]2OC(=O)C(=C)[C@H]2[C@H](O)[C@@]2(C)[C@H]1C=CC2=O |c:17| | ||
| Structure | 
| ||