| Reaction Details |
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 | Report a problem with these data |
| Target | Alkaline phosphatase, tissue-nonspecific isozyme |
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| Ligand | BDBM43817 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | SAR assay for compounds activating TNAP in the presence of 100 mM DEA performed in a luminescence assay |
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| EC50 | 199±n/a nM |
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| Citation |  PubChem, PC SAR assay for compounds activating TNAP in the presence of 100 mM DEA performed in a luminescence assay PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Alkaline phosphatase, tissue-nonspecific isozyme |
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| Name: | Alkaline phosphatase, tissue-nonspecific isozyme |
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| Synonyms: | ALPL | PPBT_HUMAN | tissue-nonspecific alkaline phosphatase precursor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 57306.17 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1448917 |
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| Residue: | 524 |
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| Sequence: | MISPFLVLAIGTCLTNSLVPEKEKDPKYWRDQAQETLKYALELQKLNTNVAKNVIMFLGD
GMGVSTVTAARILKGQLHHNPGEETRLEMDKFPFVALSKTYNTNAQVPDSAGTATAYLCG
VKANEGTVGVSAATERSRCNTTQGNEVTSILRWAKDAGKSVGIVTTTRVNHATPSAAYAH
SADRDWYSDNEMPPEALSQGCKDIAYQLMHNIRDIDVIMGGGRKYMYPKNKTDVEYESDE
KARGTRLDGLDLVDTWKSFKPRYKHSHFIWNRTELLTLDPHNVDYLLGLFEPGDMQYELN
RNNVTDPSLSEMVVVAIQILRKNPKGFFLLVEGGRIDHGHHEGKAKQALHEAVEMDRAIG
QAGSLTSSEDTLTVVTADHSHVFTFGGYTPRGNSIFGLAPMLSDTDKKPFTAILYGNGPG
YKVVGGERENVSMVDYAHNNYQAQSAVPLRHETHGGEDVAVFSKGPMAHLLHGVHEQNYV
PHVMAYAACIGANLGHCAPASSAGSLAAGPLLLALALYPLSVLF
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| BDBM43817 |
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| n/a |
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| Name | BDBM43817 |
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| Synonyms: | (3Z)-1-allyl-3-[(2-hydroxyphenyl)hydrazono]oxindole | (3Z)-3-[(2-hydroxyphenyl)hydrazinylidene]-1-prop-2-enyl-2-indolone | (3Z)-3-[(2-hydroxyphenyl)hydrazinylidene]-1-prop-2-enyl-indol-2-one | (3Z)-3-[(2-hydroxyphenyl)hydrazinylidene]-1-prop-2-enylindol-2-one | ML087 | MLS-0075347.0001 | cid_25199559 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H15N3O2 |
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| Mol. Mass. | 293.3199 |
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| SMILES | Oc1ccccc1NN=C1C(=O)N(CC=C)c2ccccc12 |w:8.8| |
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| Structure | 
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