Reaction Details |
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Target | Regulator of G-protein signaling 4 |
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Ligand | BDBM47711 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS4-Galphao. |
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EC50 | 30000±n/a nM |
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Citation | PubChem, PC Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS4-Galphao. PubChem Bioassay(2009)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Regulator of G-protein signaling 4 |
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Name: | Regulator of G-protein signaling 4 |
Synonyms: | RGP4 | RGS4 | RGS4_HUMAN | Regulator of G-protein signaling 4 (RGS4) |
Type: | Enzyme |
Mol. Mass.: | 23263.51 |
Organism: | Homo sapiens (Human) |
Description: | P49798 |
Residue: | 205 |
Sequence: | MCKGLAGLPASCLRSAKDMKHRLGFLLQKSDSCEHNSSHNKKDKVVICQRVSQEEVKKWA
ESLENLISHECGLAAFKAFLKSEYSEENIDFWISCEEYKKIKSPSKLSPKAKKIYNEFIS
VQATKEVNLDSCTREETSRNMLEPTITCFDEAQKKIFNLMEKDSYRRFLKSRFYLDLVNP
SSCGAEKQKGAKSSADCASLVPQCA
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BDBM47711 |
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n/a |
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Name | BDBM47711 |
Synonyms: | 5-methyl-2-[[oxo(3-pyridinyl)methyl]amino]-3-thiophenecarboxylic acid methyl ester | 5-methyl-2-nicotinamido-thiophene-3-carboxylic acid methyl ester | MLS000065647 | SMR000080289 | cid_1245092 | methyl 5-methyl-2-(pyridin-3-ylcarbonylamino)thiophene-3-carboxylate | methyl 5-methyl-2-(pyridine-3-carbonylamino)thiophene-3-carboxylate | methyl 5-methyl-2-[(3-pyridinylcarbonyl)amino]-3-thiophenecarboxylate |
Type | Small organic molecule |
Emp. Form. | C13H12N2O3S |
Mol. Mass. | 276.311 |
SMILES | COC(=O)c1cc(C)sc1NC(=O)c1cccnc1 |
Structure |
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