| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-lactamase |
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| Ligand | BDBM51989 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Epi-absorbance-based dose response biochemical high throughput screening assay for selective inhibitors of VIM-2 metallo-beta-lactamase |
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| IC50 | 6627±n/a nM |
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| Citation |  PubChem, PC Epi-absorbance-based dose response biochemical high throughput screening assay for selective inhibitors of VIM-2 metallo-beta-lactamase PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| Beta-lactamase |
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| Name: | Beta-lactamase |
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| Synonyms: | Beta lactamase |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 31513.38 |
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| Organism: | Pseudomonas aeruginosa |
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| Description: | gi_114881106 |
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| Residue: | 286 |
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| Sequence: | MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDKLGARVGYIELDLNSGKILESFRP
EERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVREL
CSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTM
PAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGS
RGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
|
|
|
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| BDBM51989 |
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| n/a |
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| Name | BDBM51989 |
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| Synonyms: | 3-[3-(2,4-dichlorobenzyl)oxy-2-thienyl]-4-methyl-1H-1,2,4-triazole-5-thione | 3-[3-[(2,4-dichlorophenyl)methoxy]-2-thiophenyl]-4-methyl-1H-1,2,4-triazole-5-thione | 3-[3-[(2,4-dichlorophenyl)methoxy]thiophen-2-yl]-4-methyl-1H-1,2,4-triazole-5-thione | 5-{3-[(2,4-dichlorobenzyl)oxy]-2-thienyl}-4-methyl-4H-1,2,4-triazole-3-thiol | MLS000692151 | SMR000333829 | cid_1482500 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H11Cl2N3OS2 |
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| Mol. Mass. | 372.293 |
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| SMILES | Cn1c(n[nH]c1=S)-c1sccc1OCc1ccc(Cl)cc1Cl |
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| Structure | 
|
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