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TargetBeta-lactamase
LigandBDBM51971
Substrate/Competitorn/a
Meas. Tech.Epi-absorbance-based counterscreen for selective VIM-2 inhibitors: dose response biochemical high throughput screening assay to identify inhibitors of IMP-1 metallo-beta-lactamase.
IC50 59640±n/a nM
Citation PubChem, PC Epi-absorbance-based counterscreen for selective VIM-2 inhibitors: dose response biochemical high throughput screening assay to identify inhibitors of IMP-1 metallo-beta-lactamase. PubChem Bioassay(2009)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Beta-lactamase
Name:Beta-lactamase
Synonyms:Beta-lactamase | metallo-beta-lactamase IMP-1
Type:Enzyme Catalytic Domain
Mol. Mass.:27125.88
Organism:Pseudomonas aeruginosa
Description:gi_27368096
Residue:246
Sequence:
MSKLSVFFIFLFCSIATAAESLPDLKIEKLDEGVYVHTSFEEVNGWGVVPKHGLVVLVNA
EAYLIDTPFTAKDTEKLVTWFVERGYKIKGSISSHFHSDSTGGIEWLNSRSIPTYASELT
NELLKKDGKVQATNSFSGVNYWLVKNKIEVFYPGPGHTPDNVVVWLPERKILFGGCFIKP
YGLGNLGDANIEAWPKSAKLLKSKYGKAKLVVPSHSEVGDASLLKLTLEQAVKGLNESKK
PSKPSN
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  Blast E-value cutoff:
BDBM51971
n/a
NameBDBM51971
Synonyms:3-(3-benzoxy-2-thienyl)-4-methyl-1H-1,2,4-triazole-5-thione | 4-methyl-3-(3-phenylmethoxy-2-thiophenyl)-1H-1,2,4-triazole-5-thione | 4-methyl-3-(3-phenylmethoxythiophen-2-yl)-1H-1,2,4-triazole-5-thione | 5-[3-(benzyloxy)-2-thienyl]-4-methyl-4H-1,2,4-triazol-3-ylhydrosulfide | MLS000325718 | SMR000169679 | cid_1482495
TypeSmall organic molecule
Emp. Form.C14H13N3OS2
Mol. Mass.303.403
SMILESCn1c(n[nH]c1=S)-c1sccc1OCc1ccccc1
Structure
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