Ki Summary

Reaction Details

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Target

Beta-lactamase

Ligand

BDBM51963

Substrate/Competitor

n/a

Meas. Tech.

FRET-based counterscreen for selective VIM-2 inhibitors: dose response biochemical high throughput screening assay to identify epi-absorbance assay artifacts.

IC50

1964±n/a nM

Citation

PubChem, PC FRET-based counterscreen for selective VIM-2 inhibitors: dose response biochemical high throughput screening assay to identify epi-absorbance assay artifacts. PubChem Bioassay(2009)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Beta-lactamase

Name:

Beta-lactamase

Synonyms:

Beta lactamase

Type:

Enzyme Catalytic Domain

Mol. Mass.:

31513.38

Organism:

Pseudomonas aeruginosa

Description:

gi_114881106

Residue:

286

Sequence:

MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDKLGARVGYIELDLNSGKILESFRP
EERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVREL
CSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTM
PAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGS
RGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW

BDBM51963

n/a

Name

BDBM51963

Synonyms:

MLS000557398 | N-[5-(2-Fluoro-benzylsulfanylmethyl)-[1,3,4]thiadiazol-2-yl]-2,2-dimethyl-propionamide | N-[5-[(2-fluorophenyl)methylsulfanylmethyl]-1,3,4-thiadiazol-2-yl]-2,2-dimethyl-propanamide | N-[5-[(2-fluorophenyl)methylsulfanylmethyl]-1,3,4-thiadiazol-2-yl]-2,2-dimethylpropanamide | N-[5-[[(2-fluorobenzyl)thio]methyl]-1,3,4-thiadiazol-2-yl]-2,2-dimethyl-propionamide | N-[5-[[(2-fluorophenyl)methylthio]methyl]-1,3,4-thiadiazol-2-yl]-2,2-dimethylpropanamide | SMR000148315 | cid_945654

Type

Small organic molecule

Emp. Form.

C15H18FN3OS2

Mol. Mass.

339.451

SMILES

CC(C)(C)C(=O)Nc1nnc(CSCc2ccccc2F)s1

Structure