| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-lactamase |
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| Ligand | BDBM51992 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | FRET-based counterscreen for selective VIM-2 inhibitors: dose response biochemical high throughput screening assay to identify inhibitors of IMP-1 metallo-beta-lactamase. |
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| IC50 | 59640±n/a nM |
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| Citation |  PubChem, PC FRET-based counterscreen for selective VIM-2 inhibitors: dose response biochemical high throughput screening assay to identify inhibitors of IMP-1 metallo-beta-lactamase. PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| Beta-lactamase |
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| Name: | Beta-lactamase |
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| Synonyms: | Beta-lactamase | metallo-beta-lactamase IMP-1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 27125.88 |
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| Organism: | Pseudomonas aeruginosa |
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| Description: | gi_27368096 |
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| Residue: | 246 |
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| Sequence: | MSKLSVFFIFLFCSIATAAESLPDLKIEKLDEGVYVHTSFEEVNGWGVVPKHGLVVLVNA
EAYLIDTPFTAKDTEKLVTWFVERGYKIKGSISSHFHSDSTGGIEWLNSRSIPTYASELT
NELLKKDGKVQATNSFSGVNYWLVKNKIEVFYPGPGHTPDNVVVWLPERKILFGGCFIKP
YGLGNLGDANIEAWPKSAKLLKSKYGKAKLVVPSHSEVGDASLLKLTLEQAVKGLNESKK
PSKPSN
|
|
|
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| BDBM51992 |
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| n/a |
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| Name | BDBM51992 |
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| Synonyms: | 3-[[(E)-[2-(4-bromobenzyl)oxybenzylidene]amino]thiocarbamoylamino]benzoic acid | 3-[[[2-(4-bromobenzyl)oxybenzylidene]amino]thiocarbamoylamino]benzoic acid | 3-[[[2-[(4-bromophenyl)methoxy]phenyl]methylideneamino]carbamothioylamino]benzoic acid | 3-[[[2-[[2-[(4-bromophenyl)methoxy]phenyl]methylidene]hydrazinyl]-sulfanylidenemethyl]amino]benzoic acid | 3-{[(2-{2-[(4-bromobenzyl)oxy]benzylidene}hydrazino)carbonothioyl]amino}benzoic acid | MLS000681712 | SMR000312756 | cid_16195462 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H18BrN3O3S |
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| Mol. Mass. | 484.366 |
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| SMILES | OC(=O)c1cccc(NC(=S)NN=Cc2ccccc2OCc2ccc(Br)cc2)c1 |w:12.11| |
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| Structure | 
|
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