| Reaction Details |
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 | Report a problem with these data |
| Target | POsterior Segregation |
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| Ligand | BDBM52234 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA |
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| EC50 | 260324±n/a nM |
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| Citation |  PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| POsterior Segregation |
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| Name: | POsterior Segregation |
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| Synonyms: | POsterior Segregation family member (pos-1) |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 29838.90 |
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| Organism: | Caenorhabditis elegans |
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| Description: | gi_17562800 |
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| Residue: | 264 |
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| Sequence: | MADNDFLSGEAIMVFKKEILDSHSDFTRSLSHQSASPEAYDQENVFSQDFQPFMKQDKET
QNSASQPTSEQSLANRDPCTVPDDLREEMMRQRRKEDAFKTALCDAYKRSQACSYGDQCR
FAHGVHELRLPMNPRGRNHPKYKTVLCDKFSMTGNCKYGTRCQFIHKIVDGNAAKLASGA
HANTSSKSPARNAAAHNHSLFVPQGSTDRSMDLNQSLPIRQSDLVRAFARATRLDVSGYN
STAQLAQYFESQFQRIQQLSSHHH
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| BDBM52234 |
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| n/a |
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| Name | BDBM52234 |
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| Synonyms: | 6-Amino-2-ethyl-8-(2-trifluoromethyl-phenyl)-2,6,8,8a-tetrahydro-1H-isoquinoline-5,7,7-tricarbonitrile | 6-amino-2-ethyl-8-[2-(trifluoromethyl)phenyl]-1,6,8,8a-tetrahydroisoquinoline-5,7,7-tricarbonitrile | 6-azanyl-2-ethyl-8-[2-(trifluoromethyl)phenyl]-1,6,8,8a-tetrahydroisoquinoline-5,7,7-tricarbonitrile | MLS000527680 | SMR000120254 | cid_3156453 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H18F3N5 |
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| Mol. Mass. | 397.3963 |
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| SMILES | CCN1CC2C(c3ccccc3C(F)(F)F)C(C#N)(C#N)C(N)C(C#N)=C2C=C1 |c:26,29| |
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| Structure | 
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