| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Dual specificity protein phosphatase 6 |
|---|
| Ligand | BDBM48721 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | MKP-3 in vitro HTS assay |
|---|
| IC50 | 16200±n/a nM |
|---|
| Citation |  PubChem, PC MKP-3 in vitro HTS assay PubChem Bioassay(2009)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Dual specificity protein phosphatase 6 |
|---|
| Name: | Dual specificity protein phosphatase 6 |
|---|
| Synonyms: | DUS6_RAT | Dusp6 | MAP kinase phosphatase 3 | MKP-3 | Mitogen-activated protein kinase phosphatase 3 | Mkp3 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 42303.19 |
|---|
| Organism: | Rattus norvegicus |
|---|
| Description: | gi_16758752 |
|---|
| Residue: | 381 |
|---|
| Sequence: | MIDTLRPVPFASEMAISKTVAWLNEQLELGNEQLLLMDCRPQELYESSHIESAINVAIPG
IMLRRLQKGNLPVRALFTRCEDRDRFTRRCGTDTVVLYDENSSDWNENTGGESVLGLLLK
KLKDEGCRAFYLEGGFSKFQAEFALHCETNLDGSCSSSSPPLPVLGLGGLRISSDSSSDI
ESDLDRDPNSATDSDGSPLSNSQPSFPVEILPFLYLGCAKDSTNLDVLEEFGIKYILNVT
PNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRS
VTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFERTLGLSSPCDNRVPAQ
QLYFTAPSNQNVYQVDSLQST
|
|
|
|---|
| BDBM48721 |
|---|
| n/a |
|---|
| Name | BDBM48721 |
|---|
| Synonyms: | 1-(3,4-Dichloro-phenyl)-3-(5-pyridin-4-yl-[1,3,4]thiadiazol-2-yl)-urea | 1-(3,4-dichlorophenyl)-3-(5-pyridin-4-yl-1,3,4-thiadiazol-2-yl)urea | 1-(3,4-dichlorophenyl)-3-[5-(4-pyridyl)-1,3,4-thiadiazol-2-yl]urea | MLS000559245 | SMR000178207 | cid_1075698 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C14H9Cl2N5OS |
|---|
| Mol. Mass. | 366.225 |
|---|
| SMILES | Clc1ccc(NC(=O)Nc2nnc(s2)-c2ccncc2)cc1Cl |
|---|
| Structure | 
|
|---|
Search and Browse
