| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Heat shock cognate 71 kDa protein |
|---|
| Ligand | BDBM31697 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | High Throughput Screening Assay for Hsc70 Inhibitors |
|---|
| IC50 | 999000±n/a nM |
|---|
| Citation |  PubChem, PC High Throughput Screening Assay for Hsc70 Inhibitors PubChem Bioassay(2007)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Heat shock cognate 71 kDa protein |
|---|
| Name: | Heat shock cognate 71 kDa protein |
|---|
| Synonyms: | HSC70 | HSP73 | HSP7C_HUMAN | HSPA10 | HSPA8 | heat shock 70kDa protein 8 isoform 1 | heat shock 70kDa protein 8 isoform 2 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 70887.67 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | gi_5729877 |
|---|
| Residue: | 646 |
|---|
| Sequence: | MSKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA
MNPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVS
SMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAA
IAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNH
FIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRA
RFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELN
KSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTI
PTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDI
DANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDEKQRDKVSSKN
SLESYAFNMKATVEDEKLQGKINDEDKQKILDKCNEIINWLDKNQTAEKEEFEHQQKELE
KVCNPIITKLYQSAGGMPGGMPGGFPGGGAPPSGGASSGPTIEEVD
|
|
|
|---|
| BDBM31697 |
|---|
| n/a |
|---|
| Name | BDBM31697 |
|---|
| Synonyms: | 4-[4-[2-(4-methylphenoxy)ethyl]-1-piperazinyl]-N-(5-methyl-1,3,4-thiadiazol-2-yl)-4-oxobutanamide | 4-[4-[2-(4-methylphenoxy)ethyl]piperazin-1-yl]-N-(5-methyl-1,3,4-thiadiazol-2-yl)-4-oxidanylidene-butanamide | 4-[4-[2-(4-methylphenoxy)ethyl]piperazin-1-yl]-N-(5-methyl-1,3,4-thiadiazol-2-yl)-4-oxobutanamide | 4-keto-4-[4-[2-(4-methylphenoxy)ethyl]piperazino]-N-(5-methyl-1,3,4-thiadiazol-2-yl)butyramide | MLS000082798 | SMR000059830 | cid_663757 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H27N5O3S |
|---|
| Mol. Mass. | 417.525 |
|---|
| SMILES | Cc1nnc(NC(=O)CCC(=O)N2CCN(CCOc3ccc(C)cc3)CC2)s1 |
|---|
| Structure | 
|
|---|
Search and Browse
