| Reaction Details |
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 | Report a problem with these data |
| Target | Heat shock cognate 71 kDa protein |
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| Ligand | BDBM31702 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | High Throughput Screening Assay for Hsc70 Inhibitors |
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| IC50 | 999000±n/a nM |
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| Citation |  PubChem, PC High Throughput Screening Assay for Hsc70 Inhibitors PubChem Bioassay(2007)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Heat shock cognate 71 kDa protein |
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| Name: | Heat shock cognate 71 kDa protein |
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| Synonyms: | HSC70 | HSP73 | HSP7C_HUMAN | HSPA10 | HSPA8 | heat shock 70kDa protein 8 isoform 1 | heat shock 70kDa protein 8 isoform 2 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 70887.67 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_5729877 |
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| Residue: | 646 |
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| Sequence: | MSKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA
MNPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVS
SMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAA
IAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNH
FIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRA
RFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELN
KSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTI
PTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDI
DANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDEKQRDKVSSKN
SLESYAFNMKATVEDEKLQGKINDEDKQKILDKCNEIINWLDKNQTAEKEEFEHQQKELE
KVCNPIITKLYQSAGGMPGGMPGGFPGGGAPPSGGASSGPTIEEVD
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| BDBM31702 |
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| n/a |
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| Name | BDBM31702 |
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| Synonyms: | 1-[2-(2-chloro-6-fluoro-phenyl)acetyl]isonipecotic acid ethyl ester | 1-[2-(2-chloro-6-fluorophenyl)-1-oxoethyl]-4-piperidinecarboxylic acid ethyl ester | MLS000065077 | SMR000078473 | cid_1094120 | ethyl 1-[(2-chloro-6-fluorophenyl)acetyl]-4-piperidinecarboxylate | ethyl 1-[2-(2-chloranyl-6-fluoranyl-phenyl)ethanoyl]piperidine-4-carboxylate | ethyl 1-[2-(2-chloro-6-fluorophenyl)acetyl]piperidine-4-carboxylate |
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| Type | Small organic molecule |
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| Emp. Form. | C16H19ClFNO3 |
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| Mol. Mass. | 327.778 |
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| SMILES | CCOC(=O)C1CCN(CC1)C(=O)Cc1c(F)cccc1Cl |
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| Structure | 
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