| Reaction Details |
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 | Report a problem with these data |
| Target | Heat shock cognate 71 kDa protein |
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| Ligand | BDBM31708 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | High Throughput Screening Assay for Hsc70 Inhibitors |
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| IC50 | 999000±n/a nM |
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| Citation |  PubChem, PC High Throughput Screening Assay for Hsc70 Inhibitors PubChem Bioassay(2007)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Heat shock cognate 71 kDa protein |
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| Name: | Heat shock cognate 71 kDa protein |
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| Synonyms: | HSC70 | HSP73 | HSP7C_HUMAN | HSPA10 | HSPA8 | heat shock 70kDa protein 8 isoform 1 | heat shock 70kDa protein 8 isoform 2 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 70887.67 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_5729877 |
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| Residue: | 646 |
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| Sequence: | MSKGPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVA
MNPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVS
SMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAA
IAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNH
FIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRA
RFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELN
KSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTI
PTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDI
DANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDEKQRDKVSSKN
SLESYAFNMKATVEDEKLQGKINDEDKQKILDKCNEIINWLDKNQTAEKEEFEHQQKELE
KVCNPIITKLYQSAGGMPGGMPGGFPGGGAPPSGGASSGPTIEEVD
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| BDBM31708 |
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| n/a |
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| Name | BDBM31708 |
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| Synonyms: | MLS000118949 | N-(5-methyl-1,2-oxazol-3-yl)-2-quinazolin-4-ylsulfanyl-ethanamide | N-(5-methyl-1,2-oxazol-3-yl)-2-quinazolin-4-ylsulfanylacetamide | N-(5-methyl-3-isoxazolyl)-2-(4-quinazolinylthio)acetamide | N-(5-methylisoxazol-3-yl)-2-(quinazolin-4-ylthio)acetamide | SMR000095888 | cid_2607885 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H12N4O2S |
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| Mol. Mass. | 300.336 |
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| SMILES | Cc1cc(NC(=O)CSc2ncnc3ccccc23)no1 |
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| Structure | 
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