| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Mannose-6-phosphate isomerase |
|---|
| Ligand | BDBM34592 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | HTS identification of compounds inhibiting phosphomannose isomerase (PMI) via a fluorescence intensity assay. |
|---|
| IC50 | 50000±n/a nM |
|---|
| Citation |  PubChem, PC HTS identification of compounds inhibiting phosphomannose isomerase (PMI) via a fluorescence intensity assay. PubChem Bioassay(2009)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Mannose-6-phosphate isomerase |
|---|
| Name: | Mannose-6-phosphate isomerase |
|---|
| Synonyms: | MPI | MPI protein | MPI_HUMAN | Mannose-6-phosphate isomerase | PMI1 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 46651.35 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1448919 |
|---|
| Residue: | 423 |
|---|
| Sequence: | MAAPRVFPLSCAVQQYAWGKMGSNSEVARLLASSDPLAQIAEDKPYAELWMGTHPRGDAK
ILDNRISQKTLSQWIAENQDSLGSKVKDTFNGNLPFLFKVLSVETPLSIQAHPNKELAEK
LHLQAPQHYPDANHKPEMAIALTPFQGLCGFRPVEEIVTFLKKVPEFQFLIGDEAATHLK
QTMSHDSQAVASSLQSCFSHLMKSEKKVVVEQLNLLVKRISQQAAAGNNMEDIFGELLLQ
LHQQYPGDIGCFAIYFLNLLTLKPGEAMFLEANVPHAYLKGDCVECMACSDNTVRAGLTP
KFIDVPTLCEMLSYTPSSSKDRLFLPTRSQEDPYLSIYDPPVPDFTIMKTEVPGSVTEYK
VLALDSASILLMVQGTVIASTPTTQTPIPLQRGGVLFIGANESVSLKLTEPKDLLIFRAC
CLL
|
|
|
|---|
| BDBM34592 |
|---|
| n/a |
|---|
| Name | BDBM34592 |
|---|
| Synonyms: | 5,6-bis(azanyl)-3-tert-butyl-8-[2-(hydroxymethyl)piperidin-1-yl]-2-oxidanylidene-1H-pyrrolo[2,3-c][2,7]naphthyridine-9-carbonitrile | 5,6-diamino-3-tert-butyl-2-keto-8-(2-methylolpiperidino)-1H-pyrrolo[2,3-c][2,7]naphthyridine-9-carbonitrile | 5,6-diamino-3-tert-butyl-8-[2-(hydroxymethyl)-1-piperidinyl]-2-oxo-1H-pyrrolo[2,3-c][2,7]naphthyridine-9-carbonitrile | 5,6-diamino-3-tert-butyl-8-[2-(hydroxymethyl)piperidin-1-yl]-2-oxo-1H-pyrrolo[2,3-c][2,7]naphthyridine-9-carbonitrile | MLS000097492 | SMR000067074 | cid_2998196 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H27N7O2 |
|---|
| Mol. Mass. | 409.4848 |
|---|
| SMILES | CC(C)(C)N1C(=O)Cc2c1nc(N)c1c(N)nc(N3CCCCC3CO)c(C#N)c21 |
|---|
| Structure | 
|
|---|
Search and Browse
