Reaction Details |
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Target | Mannose-6-phosphate isomerase |
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Ligand | BDBM34724 |
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Substrate/Competitor | n/a |
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Meas. Tech. | HTS identification of compounds inhibiting phosphomannose isomerase (PMI) via a fluorescence intensity assay. |
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IC50 | 50000±n/a nM |
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Citation | PubChem, PC HTS identification of compounds inhibiting phosphomannose isomerase (PMI) via a fluorescence intensity assay. PubChem Bioassay(2009)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Mannose-6-phosphate isomerase |
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Name: | Mannose-6-phosphate isomerase |
Synonyms: | MPI | MPI protein | MPI_HUMAN | Mannose-6-phosphate isomerase | PMI1 |
Type: | PROTEIN |
Mol. Mass.: | 46651.35 |
Organism: | Homo sapiens (Human) |
Description: | ChEMBL_1448919 |
Residue: | 423 |
Sequence: | MAAPRVFPLSCAVQQYAWGKMGSNSEVARLLASSDPLAQIAEDKPYAELWMGTHPRGDAK
ILDNRISQKTLSQWIAENQDSLGSKVKDTFNGNLPFLFKVLSVETPLSIQAHPNKELAEK
LHLQAPQHYPDANHKPEMAIALTPFQGLCGFRPVEEIVTFLKKVPEFQFLIGDEAATHLK
QTMSHDSQAVASSLQSCFSHLMKSEKKVVVEQLNLLVKRISQQAAAGNNMEDIFGELLLQ
LHQQYPGDIGCFAIYFLNLLTLKPGEAMFLEANVPHAYLKGDCVECMACSDNTVRAGLTP
KFIDVPTLCEMLSYTPSSSKDRLFLPTRSQEDPYLSIYDPPVPDFTIMKTEVPGSVTEYK
VLALDSASILLMVQGTVIASTPTTQTPIPLQRGGVLFIGANESVSLKLTEPKDLLIFRAC
CLL
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BDBM34724 |
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n/a |
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Name | BDBM34724 |
Synonyms: | 3-[2-[2-[(4-methylphenyl)methylidene]hydrazinyl]-2-oxoethoxy]-10-pyrido[1,2-a]indolecarboxylic acid ethyl ester | 3-[2-keto-2-[N'-(4-methylbenzylidene)hydrazino]ethoxy]pyrid[1,2-a]indole-10-carboxylic acid ethyl ester | MLS000326532 | SMR000179109 | cid_1484858 | ethyl 3-(2-{2-[(E)-(4-methylphenyl)methylidene]hydrazino}-2-oxoethoxy)pyrido[1,2-a]indole-10-carboxylate | ethyl 3-[2-[2-[(4-methylphenyl)methylidene]hydrazinyl]-2-oxidanylidene-ethoxy]pyrido[1,2-a]indole-10-carboxylate | ethyl 3-[2-[2-[(4-methylphenyl)methylidene]hydrazinyl]-2-oxoethoxy]pyrido[1,2-a]indole-10-carboxylate |
Type | Small organic molecule |
Emp. Form. | C25H23N3O4 |
Mol. Mass. | 429.4678 |
SMILES | CCOC(=O)c1c2ccc(OCC(=O)NN=Cc3ccc(C)cc3)cc2n2ccccc12 |w:15.14| |
Structure |
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