| Reaction Details |
|---|
 | Report a problem with these data |
| Target | SUMO-conjugating enzyme UBC9 |
|---|
| Ligand | BDBM51768 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | AlphaScreen confirmatory assay for validation of inhibitors of SUMOylation |
|---|
| IC50 | 1540±n/a nM |
|---|
| Citation |  PubChem, PC AlphaScreen confirmatory assay for validation of inhibitors of SUMOylation PubChem Bioassay(2010)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| SUMO-conjugating enzyme UBC9 |
|---|
| Name: | SUMO-conjugating enzyme UBC9 |
|---|
| Synonyms: | UBC9 | UBC9_HUMAN | UBCE9 | UBE2I | ubiquitin-conjugating enzyme E2I |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 18011.66 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | gi_4507785 |
|---|
| Residue: | 158 |
|---|
| Sequence: | MSGIALSRLAQERKAWRKDHPFGFVAVPTKNPDGTMNLMNWECAIPGKKGTPWEGGLFKL
RMLFKDDYPSSPPKCKFEPPLFHPNVYPSGTVCLSILEEDKDWRPAITIKQILLGIQELL
NEPNIQDPAQAEAYTIYCQNRVEYEKRVRAQAKKFAPS
|
|
|
|---|
| BDBM51768 |
|---|
| n/a |
|---|
| Name | BDBM51768 |
|---|
| Synonyms: | 2-[[5-[(4-chlorobenzyl)thio]-1,3,4-thiadiazol-2-yl]thio]-N'-[(Z)-indol-3-ylidenemethyl]acetohydrazide | 2-[[5-[(4-chlorophenyl)methylsulfanyl]-1,3,4-thiadiazol-2-yl]sulfanyl]-N'-[(Z)-indol-3-ylidenemethyl]acetohydrazide | 2-[[5-[(4-chlorophenyl)methylsulfanyl]-1,3,4-thiadiazol-2-yl]sulfanyl]-N'-[(Z)-indol-3-ylidenemethyl]ethanehydrazide | 2-[[5-[(4-chlorophenyl)methylthio]-1,3,4-thiadiazol-2-yl]thio]-N'-[(Z)-3-indolylidenemethyl]acetohydrazide | MLS000591383 | SMR000219022 | [5-(4-Chloro-benzylsulfanyl)-[1,3,4]thiadiazol-2-ylsulfanyl]-acetic acid [1-(1H-indol-3-yl)-meth-(E)-ylidene]-hydrazide | cid_5812348 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H16ClN5OS3 |
|---|
| Mol. Mass. | 474.022 |
|---|
| SMILES | Clc1ccc(CSc2nnc(SCC(=O)NN=Cc3c[nH]c4ccccc34)s2)cc1 |w:16.15| |
|---|
| Structure | 
|
|---|
Search and Browse
